Pfam Domains mapped on to the structure: 1SR9

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF08502	LeuA allosteric (dimerisation) domain	PF08502	PF08502

Conserved Domain Database Superfamily Annotations: 1SR9

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	1SR9	163680	cd07942	DRE_TIM_LeuA -	cl07974
2	1SR9	208802	cl07974	DRE_TIM_metallolyase	superfamily - -
3	1SR9	208637	LeuA_dimer	superfamily	C -
4	1SR9	208637	LeuA_dimer	superfamily	C -

Structural Details of PDB entry 1SR9 PDBid Chains Hinge Swapped Domain 1SR9 A,B A:427-433,B:427-433 A:434-643,B:434-643 Swapped-domain interface residues and interactions: Chains Residues A 434, 435, 436, 439, 440, 443, 444, 474, 477, 497, 498, 499, 500, 501, 502, 503, 504, 505, 506, 507, 508, 509, 532, 533, 534, 535, 551, 552, 553, 554, 555, 556, 557, 558, 560, 561, 562, 563, 564, 625, 626, 627, 628, 629, 633, 643, B 354, 435, 436, 497, 498, 499, 500, 501, 502, 504, 506, 507, 508, 509, 532, 533, 534, 535, 536, 540, 551, 552, 553, 554, 555, 556, 557, 558, 561, 563, 625, 626, 627, 628, 629, 631, Non-swapped-domain interface residues and interactions: Chains Residues A 18, 19, 20, 21, 22, 27, 30, 33, 34, 35, 36, 37, 38, 39, 40, 42, 43, 44, 45, 46, 47, 48, 49, 52, 61, 63, 64, 65, 67, 70, 71, 73, 84, 85, 86, 87, 88, 89, 101, 103, 104, 106, 108, 135, 137, 145, 175, 176, 178, 179, 180, 212, 218, 243, 244, 246, 254, 255, 258, 259, 260, 261, 262, 281, 288, 289, 290, 291, 292, 294, 295, 298, 299, 306, 314, 315, 316, 317, 318, 319, 326, 330, 332, 333, 334, 335, 337, 339, 340, 341, 343, 344, 347, 348, 358, 359, 361, 362, 363, 365, 366, 370, 371, 373, 374, 375, 376, 378, 379, 382, 385, 386, 389, 401, 402, 403, 405, 406, 407, 409, 410, 412, 414, 417, B 18, 19, 20, 21, 22, 27, 33, 34, 35, 36, 37, 38, 39, 40, 42, 43, 44, 45, 46, 47, 48, 49, 52, 59, 61, 63, 64, 65, 67, 71, 73, 84, 85, 86, 87, 91, 92, 93, 94, 97, 101, 103, 104, 106, 108, 135, 137, 145, 175, 176, 178, 179, 180, 218, 243, 246, 254, 255, 258, 259, 260, 261, 281, 288, 289, 290, 291, 292, 294, 295, 298, 299, 306, 314, 315, 316, 317, 318, 319, 326, 330, 332, 333, 334, 335, 337, 339, 340, 341, 343, 344, 347, 348, 350, 351, 357, 358, 359, 361, 362, 363, 365, 366, 370, 371, 373, 375, 376, 378, 379, 382, 385, 386, 389, 401, 402, 403, 405, 406, 407, 409, 410, 412, 414, 417, 425, 427,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

B:1SR9

A:1SR9

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	1SR9.ali
atm file:	1SR9.atm
cof file:	1SR9.cof
hbd file:	1SR9.hbd
html file:	1SR9.html
pdb file:	1SR9.pdb
ps file:	1SR9.ps
psa file:	1SR9.psa
rtf file:	1SR9.rtf
sst file:	1SR9.sst
tem file:	1SR9.tem