3DSwap | Knowledgebase of 3D Domain Swapping in Proteins

Pfam Domains mapped on to the structure: 1SND

No. Chain ID Pfam ID Pfam Description Linkout - Pfam Linkout - CDD

1 A PF00565 Staphylococcal nuclease homologue PF00565 PF00565

Conserved Domain Database Superfamily Annotations: 1SND

No. PDB ID PSSM ID CDD Accession Superfamily Short Name Linkout - CDD

1 1SND 29137 cd00175 SNc - cl00140

2 1SND 206856 cl00140 SNc superfamily - -

3 1SND 206856 cl00140 SNc superfamily - -

Structural Details of PDB entry 1SND

Structural Details of PDB entry 1SND

PDBid Chains Hinge Swapped Domain

1SND A,D,C,B A:112-120,D:120-121,C:120-121,B:112-120 A:121-141,D:122-141,C:122-141,B:121-141

Swapped-domain interface residues and interactions:

Chains Residues
A 38, 54, 101, 104, 105, 106, 107, 108, 110, 111, 121, 122, 123, 124, 125, 126, 128, 129, 131, 132, 135, 137, 138, 139, 140, 141,

B 54, 101, 104, 105, 106, 107, 108, 110, 111, 121, 122, 123, 124, 125, 126, 128, 129, 131, 132, 135, 137, 138, 139, 140,

Non-swapped-domain interface residues and interactions:

Chains Residues
A 7, 35, 42, 48, 77, 78, 79, 80, 81, 82, 83, 84, 85, 89, 91, 98, 109, 112, 113, 120,

B 7, 35, 37, 38, 40, 42, 78, 79, 80, 81, 82, 83, 84, 89, 91, 98, 109, 112, 113, 120,

Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.

Mutations in critical regions:

Chains Hinge Domain swapped interface Non-swapped interface Swapped Domain

A No mutation No mutation No mutation No mutation

D No mutation No mutation No mutation No mutation

C No mutation No mutation No mutation No mutation

B No mutation No mutation No mutation No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:1SND B:1SND C:1SND D:1SND

JOY Structural annotation for hinge hinge and swapped domain:

Hinge Swapped domain

JOY output:

ali file: 1SND.ali
atm file: 1SND.atm
cof file: 1SND.cof
hbd file: 1SND.hbd
html file: 1SND.html
pdb file: 1SND.pdb
ps file: 1SND.ps
psa file: 1SND.psa
rtf file: 1SND.rtf
sst file: 1SND.sst
tem file: 1SND.tem