Pfam Domains mapped on to the structure: 1SIX

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF00692	dUTPase	PF00692	PF00692

Conserved Domain Database Superfamily Annotations: 1SIX

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	1SIX	143638	cd07557	trimeric_dUTPase -	cl00493
2	1SIX	207077	cl00493	trimeric_dUTPase	superfamily - -

Structural Details of PDB entry 1SIX PDBid Chains Hinge Swapped Domain 1SIX A,B A:119-126,B:119-126 A:127-144,B:127-144 Swapped-domain interface residues and interactions: Chains Residues A 6, 7, 8, 85, 86, 87, 88, 127, 128, 129, 130, 133, 135, 136, 138, 139, 140, 141, 142, 143, 144, B 21, 22, 127, 128, 129, 130, 133, 135, 136, 138, 139, 140, 141, 142, 143, 144, C 6, 7, 8, 21, 22, 85, 86, 87, 88, Non-swapped-domain interface residues and interactions: Chains Residues A 2, 3, 4, 5, 9, 16, 17, 19, 21, 22, 23, 24, 25, 27, 40, 41, 42, 44, 50, 52, 55, 57, 58, 60, 62, 63, 65, 68, 69, 72, 74, 76, 77, 78, 79, 81, 83, 84, 93, 95, 97, 98, 99, 113, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, B 2, 3, 4, 5, 6, 7, 8, 9, 16, 17, 19, 23, 24, 25, 27, 40, 41, 42, 44, 50, 52, 55, 57, 58, 60, 62, 63, 65, 68, 69, 72, 74, 76, 77, 78, 79, 81, 83, 84, 85, 86, 87, 88, 93, 95, 97, 98, 99, 113, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, C 2, 3, 4, 5, 9, 16, 17, 19, 23, 24, 25, 27, 40, 41, 42, 44, 50, 52, 55, 57, 58, 60, 62, 63, 65, 68, 69, 72, 74, 76, 77, 78, 79, 81, 83, 84, 93, 95, 97, 98, 99, 113, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130, 133, 135, 136, 138, 139, 140, 141, 142, 143,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:1SIX

C:1SIX

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	1SIX.ali
atm file:	1SIX.atm
cof file:	1SIX.cof
hbd file:	1SIX.hbd
html file:	1SIX.html
pdb file:	1SIX.pdb
ps file:	1SIX.ps
psa file:	1SIX.psa
rtf file:	1SIX.rtf
sst file:	1SIX.sst
tem file:	1SIX.tem