Pfam Domains mapped on to the structure: 1SGK

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF02763	Diphtheria toxin, C domain	PF02763	PF02763
2	A	PF02764	Diphtheria toxin, T domain	PF02764	PF02764
3	A	PF01324	Diphtheria toxin, R domain	PF01324	PF01324

Conserved Domain Database Superfamily Annotations: 1SGK

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	1SGK	30066	cd01341	ADP_ribosyl -	cl00283
2	1SGK	206957	cl00283	ADP_ribosyl	superfamily - -
3	1SGK	66449	cl03704	Diphtheria_T	superfamily - -
4	1SGK	65145	cl03165	Diphtheria_R	superfamily - -

Structural Details of PDB entry 1SGK PDBid Chains Hinge Swapped Domain 1SGK A,B A:380-386,B:380-386 A:387-535,B:387-535 Swapped-domain interface residues and interactions: Chains Residues A 45, 46, 72, 73, 98, 100, 141, 142, 143, 144, 305, 306, 307, 308, 310, 311, 316, 317, 318, 319, 370, 371, 374, 375, 377, 379, 380, 381, 382, 387, 388, 390, 395, 399, 411, 412, 413, 417, 419, 421, 423, 424, 425, 426, 427, 428, 430, 442, 443, 444, 446, 447, 451, 452, 453, 454, 455, 456, 458, 460, 474, 475, 476, 478, 481, 482, 483, 484, 486, 488, 492, 514, 515, 517, 522, 535, B 45, 46, 72, 73, 98, 100, 141, 142, 143, 144, 305, 306, 307, 308, 310, 311, 316, 317, 318, 319, 370, 371, 374, 375, 377, 379, 380, 381, 382, 387, 388, 390, 395, 399, 411, 412, 413, 417, 419, 421, 423, 424, 425, 426, 427, 428, 430, 442, 443, 444, 446, 447, 451, 452, 453, 454, 455, 456, 458, 460, 474, 475, 476, 478, 481, 482, 483, 484, 486, 488, 492, 514, 515, 517, 522, Non-swapped-domain interface residues and interactions: Chains Residues A 44, 47, 50, 64, 65, 69, 97, 99, 140, 148, 179, 182, 272, 284, 287, 288, 309, 367, 373, 386, B 44, 47, 50, 64, 65, 69, 97, 99, 140, 148, 179, 182, 272, 284, 287, 288, 309, 367, 373, 386,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:1SGK

B:1SGK

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	1SGK.ali
atm file:	1SGK.atm
cof file:	1SGK.cof
hbd file:	1SGK.hbd
html file:	1SGK.html
pdb file:	1SGK.pdb
ps file:	1SGK.ps
psa file:	1SGK.psa
rtf file:	1SGK.rtf
sst file:	1SGK.sst
tem file:	1SGK.tem