Pfam Domains mapped on to the structure: 1SCE

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF01111	Cyclin-dependent kinase regulatory subunit	PF01111	PF01111

Conserved Domain Database Superfamily Annotations: 1SCE

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	1SCE	198805	cl03104	CKS	superfamily - -

Structural Details of PDB entry 1SCE PDBid Chains Hinge Swapped Domain 1SCE A,D,C,B A:87-90,D:88-93,C:88-93,B:87-90 A:91-102,D:94-102,C:94-102,B:91-102 Swapped-domain interface residues and interactions: Chains Residues A 35, 36, 37, 38, 39, 40, 41, 42, 43, 81, 82, 83, 84, 85, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, B 35, 36, 37, 38, 39, 40, 41, 42, 43, 81, 82, 83, 84, 85, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, C 35, 36, 37, 39, 40, 41, 42, 43, 45, 61, 62, 63, 81, 82, 83, 84, 85, 94, 95, 96, 97, 98, 99, 100, 101, D 35, 36, 37, 38, 39, 40, 41, 42, 43, 45, 48, 61, 62, 63, 81, 82, 83, 84, 85, 94, 95, 96, 97, 98, 99, 100, 101, 102, Non-swapped-domain interface residues and interactions: Chains Residues A 12, 15, 19, 22, 23, 25, 26, 27, 29, 30, 31, 32, 33, 34, 45, 48, 60, 61, 62, 63, 75, 76, 77, 78, 79, 80, 87, 89, 90, B 12, 22, 23, 25, 26, 27, 29, 30, 32, 33, 45, 48, 61, 62, 63, 75, 76, 77, 78, 79, 80, 87, 89, 90, C 32, 34, 48, 60, 76, 78, 79, 80, 87, 88, 89, 90, 92, 93, 104, 112, D 30, 76, 78, 79, 87, 89, 90, 92, 93, 104,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	No mutation	No mutation	No mutation
D	No mutation	No mutation	No mutation	No mutation
C	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:1SCE

B:1SCE

C:1SCE

D:1SCE

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	1SCE.ali
atm file:	1SCE.atm
cof file:	1SCE.cof
hbd file:	1SCE.hbd
html file:	1SCE.html
pdb file:	1SCE.pdb
ps file:	1SCE.ps
psa file:	1SCE.psa
rtf file:	1SCE.rtf
sst file:	1SCE.sst
tem file:	1SCE.tem