Pfam Domains mapped on to the structure: 1SBY

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF00106	short chain dehydrogenase	PF00106	PF00106
2	A	PF08659	KR domain	PF08659	PF08659

Conserved Domain Database Superfamily Annotations: 1SBY

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	1SBY	187584	cd05323	ADH_SDR_c_like -	cl09931
2	1SBY	212616	cl09931	NADB_Rossmann	superfamily - -
3	1SBY	212616	cl09931	NADB_Rossmann	superfamily - -

Structural Details of PDB entry 1SBY PDBid Chains Hinge Swapped Domain 1SBY A,B A:244-246,B:244-246 A:247-253,B:247-253 Swapped-domain interface residues and interactions: Chains Residues A 139, 142, 143, 145, 206, 247, 249, 250, 252, 253, B 139, 142, 143, 145, 206, 209, 247, 248, 249, 250, 252, 253, Non-swapped-domain interface residues and interactions: Chains Residues A 100, 101, 104, 108, 109, 112, 113, 116, 119, 125, 144, 146, 147, 149, 150, 153, 156, 157, 160, 161, 164, 165, 167, 168, 171, 172, 183, 195, 196, 197, 198, 205, 209, 210, 235, 237, 244, 245, 246, 254, B 100, 101, 104, 108, 109, 112, 113, 116, 119, 125, 144, 146, 147, 149, 150, 153, 156, 157, 160, 161, 164, 165, 167, 168, 171, 172, 183, 195, 196, 197, 198, 205, 235, 237, 244, 245, 246,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

B:1SBY

A:1SBY

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	1SBY.ali
atm file:	1SBY.atm
cof file:	1SBY.cof
hbd file:	1SBY.hbd
html file:	1SBY.html
pdb file:	1SBY.pdb
ps file:	1SBY.ps
psa file:	1SBY.psa
rtf file:	1SBY.rtf
sst file:	1SBY.sst
tem file:	1SBY.tem