Pfam Domains mapped on to the structure: 1RZK

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	G	PF00516	Envelope glycoprotein GP120	PF00516	PF00516
2	G	PF00516	Envelope glycoprotein GP120	PF00516	PF00516
3	G	PF00516	Envelope glycoprotein GP120	PF00516	PF00516
4	C	PF11465	Natural killer cell receptor 2B4	PF11465	PF11465
5	C	PF13895	Immunoglobulin domain	PF13895	PF13895
6	C	PF13895	Immunoglobulin domain	PF13895	PF13895
7	C	PF00047	Immunoglobulin domain	PF00047	PF00047
8	L	PF13895	Immunoglobulin domain	PF13895	PF13895
9	L	PF13895	Immunoglobulin domain	PF13895	PF13895
10	L	PF13927	Immunoglobulin domain	PF13927	PF13927
11	L	PF13927	Immunoglobulin domain	PF13927	PF13927
12	L	PF00047	Immunoglobulin domain	PF00047	PF00047
13	H	PF13927	Immunoglobulin domain	PF13927	PF13927

Conserved Domain Database Superfamily Annotations: 1RZK

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	1RZK	143182	cd04981	IgV_H -	cl11960
2	1RZK	212623	cl11960	Ig	superfamily - -
3	1RZK	143186	cd04985	IgC_CH1 -	cl11960
4	1RZK	212623	cl11960	Ig	superfamily - -
5	1RZK	212623	cl11960	Ig	superfamily - -

Structural Details of PDB entry 1RZK PDBid Chains Hinge Swapped Domain 1RZK H,L H:42-46,L:41-45 H:1-41,L:1-40 Swapped-domain interface residues and interactions: Chains Residues H 37, 39, L 36, 38, Non-swapped-domain interface residues and interactions: Chains Residues H 44, 45, 47, 50, 58, 61, 91, 100, 101, 103, 104, 122, 123, 124, 125, 127, 129, 130, 131, 137, 141, 143, 164, 166, 167, 169, 170, 172, 179, 181, 183, 209, L 43, 44, 46, 49, 55, 56, 87, 89, 91, 94, 95, 96, 98, 100, 116, 117, 118, 119, 121, 122, 123, 124, 127, 129, 131, 133, 135, 137, 160, 161, 162, 163, 164, 167, 174, 176, 178, 180, 209, 212,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
H	No mutation	No mutation	No mutation	No mutation
L	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

H:1RZK

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	1RZK.ali
atm file:	1RZK.atm
cof file:	1RZK.cof
hbd file:	1RZK.hbd
html file:	1RZK.html
pdb file:	1RZK.pdb
ps file:	1RZK.ps
psa file:	1RZK.psa
rtf file:	1RZK.rtf
sst file:	1RZK.sst
tem file:	1RZK.tem