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Pfam Domains mapped on to the structure: 1RS8

No. Chain ID Pfam ID Pfam Description Linkout - Pfam Linkout - CDD
1 A PF02898 Nitric oxide synthase, oxygenase domain PF02898 PF02898

Conserved Domain Database Superfamily Annotations: 1RS8

No. PDB ID PSSM ID CDD Accession Superfamily Short Name Linkout - CDD
1 1RS8 29667 cd00795 NOS_oxygenase_euk - cl00254
2 1RS8 206935 cl00254 NOS_oxygenase superfamily - -
Structural Details of PDB entry 1RS8

Structural Details of PDB entry 1RS8

PDBid Chains Hinge Swapped Domain
1RS8 A,B A:92-106,B:92-106 A:67-91,B:69-91

Swapped-domain interface residues and interactions:

Chains Residues
A 67, 68, 71, 72, 76, 77, 87, 88, 90, 99, 100, 372, 373,
B 69, 71, 72, 76, 77, 87, 88, 90, 372, 373,

Non-swapped-domain interface residues and interactions:

Chains Residues
A 93, 94, 96, 97, 98, 101, 102, 103, 104, 105, 106, 107, 109, 366, 367, 370, 371, 378, 392, 393, 394, 395, 397, 398, 399, 401, 402, 403, 406, 409, 413, 421, 422, 423, 424, 447, 448, 453, 454, 455, 456, 457, 458, 462, 463, 465, 466, 467, 468, 469, 482,
B 93, 94, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 109, 366, 367, 370, 371, 378, 392, 393, 394, 395, 397, 398, 399, 401, 402, 403, 406, 409, 413, 421, 422, 423, 424, 447, 448, 453, 454, 455, 456, 457, 458, 462, 463, 465, 466, 467, 468, 469,

Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.

Mutations in critical regions:

Chains Hinge Domain swapped interface Non-swapped interface Swapped Domain
AARG(100)CYS, ARG(100)CYS, No mutationNo mutation
BARG(100)CYS, No mutationARG(100)CYS, No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

Jmol_logo            Jmol_logo            Jmol_logo

2D-plot:

A:1RS8 B:1RS8

JOY Structural annotation for hinge hinge and swapped domain:

Hinge Swapped domain

JOY output:

ali file:1RS8.ali
atm file:1RS8.atm
cof file:1RS8.cof
hbd file:1RS8.hbd
html file:1RS8.html
pdb file:1RS8.pdb
ps file:1RS8.ps
psa file:1RS8.psa
rtf file:1RS8.rtf
sst file:1RS8.sst
tem file:1RS8.tem