Pfam Domains mapped on to the structure: 1ROZ
No.
Chain ID
Pfam ID
Pfam Description
Linkout - Pfam
Linkout - CDD
1
A
PF01916
Deoxyhypusine synthase
PF01916
PF01916
Gene Ontology Annotations: 1ROZ
No.
GO ID
GO Description
Linkout - AmiGO
1
GO:0008612
peptidyl-lysine modification to hypusine
GO:0008612
Conserved Domain Database Superfamily Annotations: 1ROZ
Structural Details of PDB entry 1ROZ
Structural Details of PDB entry 1ROZ
PDBid
Chains
Hinge
Swapped Domain
1ROZ
A,B
A:52-55,B:52-55
A:28-53,B:28-53
Swapped-domain interface residues and interactions:
Chains
Residues
A
28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 40 , 42 , 43 , 45 , 46 , 49 , 50 , 52 , 53 , 110 , 111 , 114 , 115 , 118 , 145 , 146 , 147 , 148 , 168 , 169 , 344 , 352 , 356 ,
B
28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 40 , 42 , 43 , 45 , 46 , 49 , 50 , 52 , 53 , 110 , 111 , 114 , 115 , 118 , 145 , 146 , 147 , 148 , 168 , 169 , 344 , 352 , 356 ,
Non-swapped-domain interface residues and interactions:
Chains
Residues
A
54 , 55 , 56 , 57 , 58 , 106 , 117 , 121 , 122 , 141 , 151 , 152 , 167 , 218 , 341 , 342 , 345 , 346 , 348 , 349 , 351 , 357 , 359 , 363 ,
B
54 , 55 , 56 , 57 , 58 , 106 , 117 , 121 , 122 , 141 , 151 , 152 , 167 , 218 , 341 , 342 , 345 , 346 , 348 , 349 , 351 , 357 ,
Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.
Mutations in critical regions:
Chains
Hinge
Domain swapped interface
Non-swapped interface
Swapped Domain
A No mutation No mutation No mutation No mutation
B No mutation No mutation No mutation No mutation
HIDE output:
JMOL Visualization:
2D-plot:
JOY Structural annotation for hinge hinge and swapped domain:
JOY output: