Pfam Domains mapped on to the structure: 1RMF

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	L	PF13895	Immunoglobulin domain	PF13895	PF13895
2	L	PF13927	Immunoglobulin domain	PF13927	PF13927

Conserved Domain Database Superfamily Annotations: 1RMF

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	1RMF	143181	cd04980	IgV_L_kappa -	cl11960
2	1RMF	212623	cl11960	Ig	superfamily - -
3	1RMF	143323	cd07699	IgC_L -	cl11960
4	1RMF	212623	cl11960	Ig	superfamily - -
5	1RMF	212623	cl11960	Ig	superfamily - -

Structural Details of PDB entry 1RMF PDBid Chains Hinge Swapped Domain 1RMF H,L H:42-46,L:46-50 H:1-41,L:1-45 Swapped-domain interface residues and interactions: Chains Residues H 35, 39, L 1, 33, 35, 37, 39, 41, 43, Non-swapped-domain interface residues and interactions: Chains Residues H 43, 44, 45, 47, 61, 62, 95, 102, 103, 104, 105, 106, 107, 108, 109, 110, 128, 129, 130, 131, 133, 134, 137, 143, 147, 149, 168, 170, 171, 172, 173, 175, 177, 182, 184, 186, 212, L 48, 49, 51, 54, 55, 60, 90, 92, 96, 99, 100, 101, 103, 105, 119, 121, 122, 123, 124, 126, 128, 129, 136, 138, 140, 142, 143, 165, 166, 167, 168, 169, 172, 179, 181, 183, 185, 212, 213, 214, 219,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
H	No mutation	GLU(39)GLN,	GLN(62)ARG, -(102)GLY, -(103)TYR, -(104)TYR, SER(105)GLY, ASP(107)ALA, THR(128)TYR,	GLN(6)GLU, ILE(30)THR, ALA(33)PRO, ILE(34)MET, GLU(39)GLN,
L	ALA(48)SER,	HIS(39)TYR,	ALA(48)SER, LEU(51)PRO, LYS(55)ARG, SER(96)GLY, LEU(101)TYR,	SER(7)THR, ASN(36)THR, HIS(39)TYR, SER(45)PRO,

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

H:1RMF

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	1RMF.ali
atm file:	1RMF.atm
cof file:	1RMF.cof
hbd file:	1RMF.hbd
html file:	1RMF.html
pdb file:	1RMF.pdb
ps file:	1RMF.ps
psa file:	1RMF.psa
rtf file:	1RMF.rtf
sst file:	1RMF.sst
tem file:	1RMF.tem