Pfam Domains mapped on to the structure: 1R1U

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF12840	Helix-turn-helix domain	PF12840	PF12840
2	A	PF01022	Bacterial regulatory protein, arsR family	PF01022	PF01022

Conserved Domain Database Superfamily Annotations: 1R1U

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	1R1U	28974	cd00090	HTH_ARSR -	cl00088
2	1R1U	212173	cl00088	HTH	superfamily - -

Structural Details of PDB entry 1R1U PDBid Chains Hinge Swapped Domain 1R1U A,D,C,B A:82-84,D:82-84,C:82-84,B:82-84 A:85-103,D:85-103,C:85-103,B:85-103 Swapped-domain interface residues and interactions: Chains Residues A 12, 15, 16, 86, 87, 89, 90, 93, 94, 95, 96, 97, 98, 99, 100, 102, B 12, 15, 16, 86, 87, 89, 90, 93, 94, 95, 96, 97, 98, 99, 101, C 12, 15, 16, 86, 87, 89, 90, 93, 94, 95, 96, 97, 98, 99, 100, 102, 103, D 12, 15, 16, 86, 87, 89, 90, 93, 94, 95, 96, 97, 98, 99, 100, 102, Non-swapped-domain interface residues and interactions: Chains Residues A 10, 13, 14, 17, 19, 20, 21, 23, 24, 25, 26, 27, 28, 29, 30, 33, 50, 51, 52, 54, 55, 58, 59, 62, 67, 84, B 10, 13, 14, 17, 19, 20, 21, 23, 24, 25, 26, 27, 28, 29, 30, 33, 50, 51, 52, 54, 55, 58, 59, 62, 67, 83, 84, C 6, 7, 8, 10, 13, 14, 17, 19, 20, 21, 23, 24, 25, 26, 27, 28, 29, 30, 33, 50, 51, 52, 54, 55, 58, 59, 61, 62, 67, 83, 84, D 10, 13, 14, 17, 19, 20, 21, 23, 24, 25, 26, 27, 28, 29, 30, 33, 37, 48, 50, 51, 52, 54, 55, 58, 59, 62, 67, 83, 84,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	No mutation	No mutation	No mutation
D	No mutation	No mutation	No mutation	No mutation
C	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:1R1U

B:1R1U

C:1R1U

D:1R1U

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	1R1U.ali
atm file:	1R1U.atm
cof file:	1R1U.cof
hbd file:	1R1U.hbd
html file:	1R1U.html
pdb file:	1R1U.pdb
ps file:	1R1U.ps
psa file:	1R1U.psa
rtf file:	1R1U.rtf
sst file:	1R1U.sst
tem file:	1R1U.tem