3DSwap | Knowledgebase of 3D Domain Swapping in Proteins

Pfam Domains mapped on to the structure: 1QAG

No. Chain ID Pfam ID Pfam Description Linkout - Pfam Linkout - CDD

1 A PF00307 Calponin homology (CH) domain PF00307 PF00307

2 A PF00307 Calponin homology (CH) domain PF00307 PF00307

3 A PF11971 CAMSAP CH domain PF11971 PF11971

Gene Ontology Annotations: 1QAG

No. GO ID GO Description Linkout - AmiGO

1 GO:0005515 protein binding GO:0005515

Conserved Domain Database Superfamily Annotations: 1QAG

No. PDB ID PSSM ID CDD Accession Superfamily Short Name Linkout - CDD

1 1QAG 28898 cd00014 CH - cl00030

2 1QAG 206790 cl00030 CH superfamily - -

3 1QAG 28898 cd00014 CH - cl00030

4 1QAG 206790 cl00030 CH superfamily - -

Structural Details of PDB entry 1QAG

Structural Details of PDB entry 1QAG

PDBid Chains Hinge Swapped Domain

1QAG A,B A:136-152,B:136-152 A:153-256,B:153-256

Swapped-domain interface residues and interactions:

Chains Residues
A 33, 36, 39, 40, 43, 136, 139, 143, 147, 155, 156, 158, 159, 162, 223, 224, 225, 226, 227, 228, 229, 232, 239, 241, 242, 244, 248, 249, 251, 252, 256,

B 33, 36, 39, 40, 43, 136, 139, 143, 147, 154, 155, 156, 158, 159, 162, 165, 223, 224, 225, 226, 227, 228, 229, 232, 239, 241, 242, 244, 248, 249, 251, 252,

Non-swapped-domain interface residues and interactions:

Chains Residues
A 32, 35, 37, 46, 47, 128, 135, 141, 142, 145, 146, 148, 149, 150, 151, 152,

B 32, 35, 37, 46, 47, 128, 135, 137, 141, 142, 146, 149, 150,

Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.

Mutations in critical regions:

Chains Hinge Domain swapped interface Non-swapped interface Swapped Domain

A No mutation No mutation No mutation No mutation

B No mutation No mutation No mutation No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:1QAG B:1QAG

JOY Structural annotation for hinge hinge and swapped domain:

Hinge Swapped domain

JOY output:

ali file: 1QAG.ali
atm file: 1QAG.atm
cof file: 1QAG.cof
hbd file: 1QAG.hbd
html file: 1QAG.html
pdb file: 1QAG.pdb
ps file: 1QAG.ps
psa file: 1QAG.psa
rtf file: 1QAG.rtf
sst file: 1QAG.sst
tem file: 1QAG.tem