Pfam Domains mapped on to the structure: 1OV3

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF07653	Variant SH3 domain	PF07653	PF07653
2	A	PF07653	Variant SH3 domain	PF07653	PF07653
3	A	PF00018	SH3 domain	PF00018	PF00018
4	A	PF00018	SH3 domain	PF00018	PF00018

Gene Ontology Annotations: 1OV3

No.	GO ID	GO Description	Linkout - AmiGO
1	GO:0005515	protein binding	GO:0005515

Structural Details of PDB entry 1OV3 PDBid Chains Hinge Swapped Domain 1OV3 A,B A:197-204,B:197-204 A:150-196,B:152-196 Swapped-domain interface residues and interactions: Chains Residues A 150, 151, 152, 153, 155, 160, 161, 162, 163, 164, 165, 166, 167, 173, 174, 175, 177, 182, 183, 186, 187, 189, 190, 191, 192, 193, 194, 195, 196, 201, 202, 203, 204, 205, 206, 207, 209, 210, 211, 212, 213, 260, 261, 262, 277, 278, B 152, 153, 154, 155, 156, 157, 160, 161, 162, 163, 164, 165, 166, 167, 173, 174, 175, 177, 183, 187, 189, 190, 191, 192, 193, 194, 195, 196, 202, 203, 204, 205, 206, 207, 209, 210, 211, 212, 213, 260, 261, 262, 277, 278, Non-swapped-domain interface residues and interactions: Chains Residues A 197, 198, 200, 208, 220, 264, 283, B 197, 198, 200, 201, 208, 264,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	LEU(150)-, GLY(151)-, SER(152)-, PRO(153)-, PHE(155)-,	No mutation	LEU(150)-, GLY(151)-, SER(152)-, PRO(153)-, GLU(154)-, PHE(155)-,
B	No mutation	SER(152)-, PRO(153)-, GLU(154)-, PHE(155)-,	No mutation	SER(152)-, PRO(153)-, GLU(154)-, PHE(155)-,

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:1OV3

B:1OV3

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	1OV3.ali
atm file:	1OV3.atm
cof file:	1OV3.cof
hbd file:	1OV3.hbd
html file:	1OV3.html
pdb file:	1OV3.pdb
ps file:	1OV3.ps
psa file:	1OV3.psa
rtf file:	1OV3.rtf
sst file:	1OV3.sst
tem file:	1OV3.tem