Pfam Domains mapped on to the structure: 1O5Q

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF13714	Phosphoenolpyruvate phosphomutase	PF13714	PF13714
2	A	PF00463	Isocitrate lyase family	PF00463	PF00463

Conserved Domain Database Superfamily Annotations: 1O5Q

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	1O5Q	119340	cd00377	ICL_PEPM -	cl00435
2	1O5Q	212216	cl00435	ICL_KPHMT	superfamily - -
3	1O5Q	212216	cl00435	ICL_KPHMT	superfamily - -

Structural Details of PDB entry 1O5Q PDBid Chains Hinge Swapped Domain 1O5Q A,D,C,B A:235-236,D:235-236,C:235-236,B:235-236 A:237-286,D:237-286,C:237-286,B:237-286 Swapped-domain interface residues and interactions: Chains Residues A 33, 34, 37, 51, 55, 56, 57, 214, 219, 221, 222, 238, 239, 240, 241, 242, 243, 244, 245, 246, 247, 248, 250, 251, 252, 254, 255, 258, 259, 260, 261, 264, 265, 266, 267, 268, 269, 270, 272, 273, 277, 279, 282, 283, 285, 286, B 33, 34, 37, 55, 56, 57, 214, 219, 221, 222, 238, 239, 240, 241, 242, 243, 244, 245, 246, 247, 248, 250, 251, 252, 254, 255, 258, 259, 260, 261, 264, 265, 266, 267, 268, 269, 270, 272, 273, 277, 279, 282, 283, C 33, 34, 37, 51, 55, 56, 57, 214, 219, 221, 222, 238, 239, 240, 241, 242, 243, 244, 245, 246, 247, 248, 250, 251, 252, 254, 255, 258, 259, 260, 261, 264, 265, 266, 267, 268, 269, 270, 272, 273, 277, 279, 282, 285, 286, D 33, 34, 37, 51, 55, 56, 57, 93, 94, 214, 219, 221, 222, 238, 239, 240, 241, 242, 243, 244, 245, 246, 247, 248, 250, 251, 252, 254, 255, 258, 259, 260, 261, 264, 265, 266, 267, 268, 269, 270, 272, 273, 277, 279, Non-swapped-domain interface residues and interactions: Chains Residues A 17, 21, 23, 27, 28, 29, 30, 38, 39, 52, 53, 54, 58, 59, 60, 61, 63, 64, 65, 66, 69, 72, 73, 76, 77, 95, 96, 99, 106, 107, 108, 149, 213, 215, 235, B 17, 21, 23, 24, 27, 28, 29, 30, 38, 39, 51, 52, 53, 54, 58, 59, 60, 61, 63, 64, 65, 66, 69, 72, 73, 76, 77, 93, 94, 95, 96, 99, 103, 106, 107, 108, 139, 213, 215, 235, C 17, 21, 23, 27, 28, 29, 30, 38, 39, 52, 53, 54, 59, 60, 61, 63, 64, 65, 66, 69, 72, 73, 76, 77, 95, 96, 99, 103, 106, 107, 108, 213, 215, 235, 289, D 4, 17, 21, 23, 27, 28, 29, 30, 38, 39, 52, 53, 54, 59, 60, 61, 63, 64, 65, 66, 69, 72, 73, 76, 77, 95, 96, 99, 106, 107, 108, 213, 215, 235,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	No mutation	No mutation	No mutation
D	No mutation	No mutation	No mutation	No mutation
C	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:1O5Q

B:1O5Q

C:1O5Q

D:1O5Q

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	1O5Q.ali
atm file:	1O5Q.atm
cof file:	1O5Q.cof
hbd file:	1O5Q.hbd
html file:	1O5Q.html
pdb file:	1O5Q.pdb
ps file:	1O5Q.ps
psa file:	1O5Q.psa
rtf file:	1O5Q.rtf
sst file:	1O5Q.sst
tem file:	1O5Q.tem