Pfam Domains mapped on to the structure: 1O5O
No.
Chain ID
Pfam ID
Pfam Description
Linkout - Pfam
Linkout - CDD
1
A
PF00156
Phosphoribosyl transferase domain
PF00156
PF00156
Gene Ontology Annotations: 1O5O
Conserved Domain Database Superfamily Annotations: 1O5O
Structural Details of PDB entry 1O5O
Structural Details of PDB entry 1O5O
PDBid
Chains
Hinge
Swapped Domain
1O5O
A,D,C,B
A:46-49,D:46-49,C:46-49,B:46-49
A:50-66,D:50-66,C:50-66,B:50-66
Swapped-domain interface residues and interactions:
Chains
Residues
A
10 , 13 , 14 , 17 , 20 , 21 , 22 , 50 , 55 , 56 , 57 , 58 , 59 , 60 , 62 , 64 , 65 , 66 , 195 , 196 , 198 , 199 ,
B
10 , 13 , 14 , 17 , 20 , 21 , 22 , 50 , 55 , 56 , 57 , 58 , 59 , 60 , 62 , 64 , 65 , 66 , 195 , 196 , 199 ,
C
10 , 13 , 14 , 17 , 20 , 21 , 22 , 50 , 55 , 56 , 57 , 58 , 59 , 60 , 62 , 64 , 65 , 66 , 195 , 196 , 199 ,
D
10 , 13 , 14 , 17 , 20 , 21 , 22 , 50 , 55 , 56 , 57 , 58 , 59 , 60 , 62 , 64 , 65 , 66 , 195 , 196 , 199 ,
Non-swapped-domain interface residues and interactions:
Chains
Residues
A
7 , 8 , 9 , 11 , 15 , 27 , 30 , 31 , 34 , 35 , 38 , 39 , 42 , 43 , 45 , 46 , 48 , 67 , 69 , 70 , 78 , 79 , 82 , 86 , 89 , 90 , 91 , 92 , 93 , 94 , 95 , 96 , 97 , 99 , 103 , 114 , 115 , 117 , 118 , 119 , 120 , 189 , 206 , 207 , 208 , 209 ,
B
8 , 9 , 11 , 15 , 27 , 30 , 31 , 34 , 35 , 38 , 39 , 42 , 43 , 45 , 46 , 48 , 67 , 69 , 70 , 78 , 79 , 82 , 86 , 89 , 90 , 91 , 92 , 93 , 94 , 95 , 96 , 97 , 99 , 114 , 115 , 117 , 118 , 119 , 120 , 189 , 206 , 207 , 208 , 209 ,
C
7 , 8 , 9 , 11 , 15 , 27 , 30 , 31 , 34 , 35 , 38 , 39 , 42 , 43 , 45 , 46 , 48 , 67 , 69 , 70 , 78 , 79 , 82 , 86 , 89 , 90 , 91 , 92 , 93 , 94 , 95 , 96 , 97 , 99 , 103 , 114 , 115 , 117 , 118 , 119 , 120 , 189 , 206 , 207 , 208 , 209 ,
D
8 , 9 , 11 , 15 , 27 , 30 , 31 , 34 , 35 , 38 , 39 , 42 , 43 , 45 , 46 , 48 , 67 , 69 , 70 , 78 , 79 , 82 , 86 , 89 , 90 , 91 , 92 , 93 , 94 , 95 , 96 , 97 , 99 , 114 , 115 , 117 , 118 , 119 , 120 , 189 , 206 , 207 , 208 ,
Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.
Mutations in critical regions:
Chains
Hinge
Domain swapped interface
Non-swapped interface
Swapped Domain
A No mutation No mutation No mutation No mutation
D No mutation No mutation No mutation No mutation
C No mutation No mutation No mutation No mutation
B No mutation No mutation No mutation No mutation
HIDE output:
JMOL Visualization:
2D-plot:
JOY Structural annotation for hinge hinge and swapped domain:
JOY output: