Pfam Domains mapped on to the structure: 1NZY

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF00378	Enoyl-CoA hydratase/isomerase family	PF00378	PF00378
2	B	PF00378	Enoyl-CoA hydratase/isomerase family	PF00378	PF00378

Conserved Domain Database Superfamily Annotations: 1NZY

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	1NZY	119339	cd06558	crotonase-like -	cl15762
2	1NZY	210162	cl15762	crotonase-like	superfamily - -
3	1NZY	210162	cl15762	crotonase-like	superfamily - -

Structural Details of PDB entry 1NZY PDBid Chains Hinge Swapped Domain 1NZY A,C,B A:222-226,C:222-226,B:222-226 A:227-269,C:227-269,B:227-269 Swapped-domain interface residues and interactions: Chains Residues A 75, 79, 82, 86, 90, 139, 140, 141, 142, 143, 144, 145, 147, 149, 150, 166, 167, 168, 169, 227, 228, 229, 230, 231, 232, 233, 234, 235, 236, 237, 239, 240, 241, 244, 245, 246, 248, 249, 252, 253, 258, 259, 260, 261, 262, 263, 265, 269, B 75, 79, 82, 86, 90, 134, 136, 139, 140, 141, 142, 143, 144, 145, 147, 149, 150, 167, 168, 169, 170, 227, 228, 229, 230, 231, 232, 233, 234, 235, 236, 237, 239, 240, 241, 245, 246, 248, 249, 252, 253, 258, 261, 262, 263, 265, 269, C 75, 79, 82, 86, 90, 134, 136, 139, 140, 141, 142, 143, 144, 145, 147, 149, 150, 167, 168, 169, 227, 228, 229, 230, 231, 232, 233, 234, 236, 237, 239, 240, 241, 245, 246, 248, 249, 252, 253, 258, 259, 260, 261, 262, 263, 265, 269, D 224, 226, 227, E 224, 226, 227, F 224, 226, 227, Non-swapped-domain interface residues and interactions: Chains Residues A 40, 44, 66, 67, 69, 71, 78, 83, 87, 88, 91, 94, 97, 98, 100, 102, 119, 122, 123, 124, 125, 138, 153, 154, 155, 157, 158, 159, 160, 161, 162, 163, 165, 175, 177, 178, 180, 181, 183, 184, 202, 206, 209, 210, 212, 213, 214, 216, 217, 218, 220, 221, 222, 223, 224, 225, 226, B 40, 41, 44, 66, 67, 69, 71, 78, 80, 83, 87, 88, 91, 94, 97, 98, 100, 122, 123, 124, 125, 132, 138, 153, 154, 155, 157, 158, 159, 160, 161, 162, 163, 165, 166, 175, 177, 178, 180, 183, 184, 202, 209, 210, 212, 213, 214, 216, 217, 218, 220, 221, 222, 223, 224, 225, 226, C 40, 41, 44, 66, 67, 69, 71, 78, 80, 83, 87, 88, 91, 94, 95, 97, 98, 100, 122, 123, 124, 125, 132, 138, 153, 154, 155, 157, 158, 159, 160, 161, 162, 163, 165, 166, 170, 177, 178, 180, 183, 184, 202, 206, 209, 210, 212, 213, 214, 216, 217, 218, 220, 221, 222, 223, 224, 225, 226, D 40, 44, 66, 67, 69, 71, 75, 78, 79, 82, 83, 86, 87, 88, 90, 91, 94, 97, 98, 100, 102, 119, 122, 123, 124, 125, 138, 139, 140, 141, 142, 143, 144, 145, 147, 149, 150, 153, 154, 155, 157, 158, 159, 160, 161, 162, 163, 165, 166, 167, 168, 169, 175, 177, 178, 180, 181, 183, 184, 202, 206, 209, 210, 212, 213, 214, 216, 217, 218, 220, 221, 222, 223, 225, 228, 229, 230, 231, 232, 233, 234, 235, 236, 237, 239, 240, 241, 244, 245, 246, 248, 249, 252, 253, 258, 259, 260, 261, 262, 263, 265, 269, E 40, 41, 44, 66, 67, 69, 71, 75, 78, 79, 80, 82, 83, 86, 87, 88, 90, 91, 94, 97, 98, 100, 122, 123, 124, 125, 132, 134, 136, 138, 139, 140, 141, 142, 143, 144, 145, 147, 149, 150, 153, 154, 155, 157, 158, 159, 160, 161, 162, 163, 165, 166, 167, 168, 169, 170, 175, 177, 178, 180, 183, 184, 202, 209, 210, 212, 213, 214, 216, 217, 218, 220, 221, 222, 223, 225, 228, 229, 230, 231, 232, 233, 234, 235, 236, 237, 239, 240, 241, 245, 246, 248, 249, 252, 253, 258, 261, 262, 263, 265, 269, F 40, 41, 44, 66, 67, 69, 71, 75, 78, 79, 80, 82, 83, 86, 87, 88, 90, 91, 94, 95, 97, 98, 100, 122, 123, 124, 125, 132, 134, 136, 138, 139, 140, 141, 142, 143, 144, 145, 147, 149, 150, 153, 154, 155, 157, 158, 159, 160, 161, 162, 163, 165, 166, 167, 168, 169, 170, 177, 178, 180, 183, 184, 202, 206, 209, 210, 212, 213, 214, 216, 217, 218, 220, 221, 222, 223, 225, 228, 229, 230, 231, 232, 233, 234, 236, 237, 239, 240, 241, 245, 246, 248, 249, 252, 253, 258, 259, 260, 261, 262, 263, 265,

Swapped domains are represented using trasperent spheres. Non-swapped part is reprented using light color and cartoon reprentation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	No mutation	No mutation	No mutation
C	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

3:1NZY

A:1NZY

F:1NZY

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	1NZY.ali
atm file:	1NZY.atm
cof file:	1NZY.cof
hbd file:	1NZY.hbd
html file:	1NZY.html
pdb file:	1NZY.pdb
ps file:	1NZY.ps
psa file:	1NZY.psa
rtf file:	1NZY.rtf
sst file:	1NZY.sst
tem file:	1NZY.tem