Pfam Domains mapped on to the structure: 1NIR

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF13442	Cytochrome C oxidase, cbb3-type, subunit III	PF13442	PF13442
2	A	PF00034	Cytochrome c	PF00034	PF00034
3	A	PF02239	Cytochrome D1 heme domain	PF02239	PF02239

Gene Ontology Annotations: 1NIR

No.	GO ID	GO Description	Linkout - AmiGO
1	GO:0020037	heme binding	GO:0020037

Conserved Domain Database Superfamily Annotations: 1NIR

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	1NIR	212313	cl11414	Cytochrom_C	superfamily - -
2	1NIR	212313	cl11414	Cytochrom_C	superfamily - -

Structural Details of PDB entry 1NIR PDBid Chains Hinge Swapped Domain 1NIR A,B A:26-26,B:26-26 A:6-25,B:5-25 Swapped-domain interface residues and interactions: Chains Residues A 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 19, 21, 22, 23, 24, 40, 41, 44, 45, 46, 48, 49, 50, 87, 89, 114, 115, 116, 117, 198, 222, 223, 390, 422, 441, 443, B 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 19, 21, 22, 23, 24, 40, 41, 44, 45, 46, 48, 49, 50, 87, 89, 114, 115, 116, 117, 198, 222, 223, 390, 422, 441, 443, Non-swapped-domain interface residues and interactions: Chains Residues A 31, 36, 53, 90, 111, 118, 120, 121, 122, 156, 249, 262, 263, 265, 267, 268, 269, 273, 274, 275, 276, 314, 315, 316, 317, 318, 319, 320, 321, 327, 343, 344, 357, 367, 369, 424, 543, B 31, 33, 36, 53, 111, 118, 120, 121, 122, 156, 249, 262, 263, 265, 267, 268, 269, 273, 274, 275, 276, 314, 315, 316, 317, 318, 319, 320, 321, 327, 344, 357, 367, 369, 424,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

B:1NIR

A:1NIR

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	1NIR.ali
atm file:	1NIR.atm
cof file:	1NIR.cof
hbd file:	1NIR.hbd
html file:	1NIR.html
pdb file:	1NIR.pdb
ps file:	1NIR.ps
psa file:	1NIR.psa
rtf file:	1NIR.rtf
sst file:	1NIR.sst
tem file:	1NIR.tem