3DSwap | Knowledgebase of 3D Domain Swapping in Proteins

Pfam Domains mapped on to the structure: 1N8Z

No. Chain ID Pfam ID Pfam Description Linkout - Pfam Linkout - CDD

1 A PF13895 Immunoglobulin domain PF13895 PF13895

2 A PF13895 Immunoglobulin domain PF13895 PF13895

3 A PF13927 Immunoglobulin domain PF13927 PF13927

4 A PF13927 Immunoglobulin domain PF13927 PF13927

5 A PF00047 Immunoglobulin domain PF00047 PF00047

6 C PF01030 Receptor L domain PF01030 PF01030

7 C PF01030 Receptor L domain PF01030 PF01030

Conserved Domain Database Superfamily Annotations: 1N8Z

No. PDB ID PSSM ID CDD Accession Superfamily Short Name Linkout - CDD

1 1N8Z 201561 cl08303 Recep_L_domain superfamily - -

2 1N8Z 201561 cl08303 Recep_L_domain superfamily - -

3 1N8Z 198491 cl00066 FU superfamily - -

4 1N8Z 198491 cl00066 FU superfamily - -

5 1N8Z 198491 cl00066 FU superfamily - -

6 1N8Z 198491 cl00066 FU superfamily - -

Structural Details of PDB entry 1N8Z

Structural Details of PDB entry 1N8Z

PDBid Chains Hinge Swapped Domain

1N8Z A,B A:41-45,B:42-46 A:1-40,B:1-41

Swapped-domain interface residues and interactions:

Chains Residues
A 36, 38,

B 39,

Non-swapped-domain interface residues and interactions:

Chains Residues
A 42, 43, 44, 46, 49, 55, 87, 89, 91, 94, 95, 96, 98, 100, 114, 116, 117, 118, 119, 121, 123, 124, 127, 129, 131, 133, 135, 137, 138, 160, 161, 162, 163, 164, 167, 174, 176, 178, 180, 207, 208, 209, 214,

B 44, 45, 47, 50, 59, 95, 99, 104, 105, 106, 107, 108, 110, 111, 112, 129, 130, 131, 132, 134, 136, 137, 138, 139, 144, 148, 150, 171, 173, 174, 176, 177, 178, 186, 188, 190, 216,

Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.

Mutations in critical regions:

Chains Hinge Domain swapped interface Non-swapped interface Swapped Domain

A No mutation No mutation No mutation No mutation

B No mutation No mutation No mutation No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:1N8Z B:1N8Z

JOY Structural annotation for hinge hinge and swapped domain:

Hinge Swapped domain

JOY output:

ali file: 1N8Z.ali
atm file: 1N8Z.atm
cof file: 1N8Z.cof
hbd file: 1N8Z.hbd
html file: 1N8Z.html
pdb file: 1N8Z.pdb
ps file: 1N8Z.ps
psa file: 1N8Z.psa
rtf file: 1N8Z.rtf
sst file: 1N8Z.sst
tem file: 1N8Z.tem