3DSwap | Knowledgebase of 3D Domain Swapping in Proteins

Pfam Domains mapped on to the structure: 1N1J

No. Chain ID Pfam ID Pfam Description Linkout - Pfam Linkout - CDD

1 A PF00808 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PF00808 PF00808

2 A PF00125 Core histone H2A/H2B/H3/H4 PF00125 PF00125

3 B PF00125 Core histone H2A/H2B/H3/H4 PF00125 PF00125

4 B PF00808 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PF00808 PF00808

Conserved Domain Database Superfamily Annotations: 1N1J

No. PDB ID PSSM ID CDD Accession Superfamily Short Name Linkout - CDD

1 1N1J 206819 cl00074 H2A superfamily - -

Structural Details of PDB entry 1N1J

Structural Details of PDB entry 1N1J

PDBid Chains Hinge Swapped Domain

1N1J A,B A:71-74,B:71-74;A:58-61,B:58-61 A:55-70,B:55-70

Swapped-domain interface residues and interactions:

Chains Residues
A 55, 56, 57, 58, 61, 62, 65, 66, 69, 70, 100, 109, 110, 111, 112, 113, 116, 132, 136,

B 43, 47, 51, 55, 57, 58, 60, 61, 62, 64, 65, 67, 68, 69, 70, 74, 77, 78, 81, 82,

Non-swapped-domain interface residues and interactions:

Chains Residues
A 71, 73, 74, 75, 76, 77, 79, 80, 83, 84, 86, 87, 88, 89, 90, 91, 92, 93, 94, 96, 97, 117, 120, 124, 125, 127, 128, 131, 135, 139, 140, 141,

B 44, 45, 48, 50, 52, 54, 71, 72, 73, 75, 76, 80, 85, 94, 95, 96, 97, 98, 101, 110, 113, 114, 117, 118,

Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.

Mutations in critical regions:

Chains Hinge Domain swapped interface Non-swapped interface Swapped Domain

A No mutation No mutation No mutation No mutation

B No mutation No mutation No mutation No mutation

B No mutation No mutation No mutation No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:1N1J B:1N1J

JOY Structural annotation for hinge hinge and swapped domain:

Hinge Swapped domain

JOY output:

ali file: 1N1J.ali
atm file: 1N1J.atm
cof file: 1N1J.cof
hbd file: 1N1J.hbd
html file: 1N1J.html
pdb file: 1N1J.pdb
ps file: 1N1J.ps
psa file: 1N1J.psa
rtf file: 1N1J.rtf
sst file: 1N1J.sst
tem file: 1N1J.tem