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Pfam Domains mapped on to the structure: 1MKK

No. Chain ID Pfam ID Pfam Description Linkout - Pfam Linkout - CDD
1 A PF00341 Platelet-derived growth factor (PDGF) PF00341 PF00341

Conserved Domain Database Superfamily Annotations: 1MKK

No. PDB ID PSSM ID CDD Accession Superfamily Short Name Linkout - CDD
1 1MKK 29041 cd00135 PDGF - cl00116
2 1MKK 206845 cl00116 PDGF superfamily - -
Structural Details of PDB entry 1MKK

Structural Details of PDB entry 1MKK

PDBid Chains Hinge Swapped Domain
1MKK A,B A:26-28,B:26-28 A:14-25,B:14-25

Swapped-domain interface residues and interactions:

Chains Residues
A 14, 15, 16, 17, 20, 21, 23, 24, 49, 51, 53, 77, 78, 79,
B 14, 15, 16, 17, 20, 21, 23, 24, 49, 51, 53, 77, 78, 79,

Non-swapped-domain interface residues and interactions:

Chains Residues
A 27, 29, 30, 32, 34, 48, 50, 59, 60, 61, 76, 81, 91, 93, 106,
B 13, 27, 29, 30, 32, 34, 48, 50, 59, 60, 61, 76, 81, 91, 93,

Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.

Mutations in critical regions:

Chains Hinge Domain swapped interface Non-swapped interface Swapped Domain
ANo mutationNo mutationALA(61)CYS, No mutation
BNo mutationNo mutationMET(13)-, ALA(61)CYS, No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

Jmol_logo            Jmol_logo            Jmol_logo

2D-plot:

A:1MKK B:1MKK

JOY Structural annotation for hinge hinge and swapped domain:

Hinge Swapped domain

JOY output:

ali file:1MKK.ali
atm file:1MKK.atm
cof file:1MKK.cof
hbd file:1MKK.hbd
html file:1MKK.html
pdb file:1MKK.pdb
ps file:1MKK.ps
psa file:1MKK.psa
rtf file:1MKK.rtf
sst file:1MKK.sst
tem file:1MKK.tem