Pfam Domains mapped on to the structure: 1MIM

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	L	PF13927	Immunoglobulin domain	PF13927	PF13927
2	L	PF13927	Immunoglobulin domain	PF13927	PF13927
3	L	PF13895	Immunoglobulin domain	PF13895	PF13895
4	L	PF13895	Immunoglobulin domain	PF13895	PF13895
5	L	PF00047	Immunoglobulin domain	PF00047	PF00047
6	H	PF13895	Immunoglobulin domain	PF13895	PF13895
7	H	PF13927	Immunoglobulin domain	PF13927	PF13927

Conserved Domain Database Superfamily Annotations: 1MIM

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	1MIM	143323	cd07699	IgC_L -	cl11960
2	1MIM	212623	cl11960	Ig	superfamily - -
3	1MIM	212623	cl11960	Ig	superfamily - -
4	1MIM	212623	cl11960	Ig	superfamily - -

Structural Details of PDB entry 1MIM PDBid Chains Hinge Swapped Domain 1MIM H,L H:39-43,L:39-43 H:1-38,L:1-38 Swapped-domain interface residues and interactions: Chains Residues H 33, 37, L 1, 31, 33, 35, 37, Non-swapped-domain interface residues and interactions: Chains Residues H 42, 43, 45, 60, 93, 97, 99, 100, 101, 102, 103, 104, 105, 107, 124, 125, 126, 127, 129, 130, 131, 137, 139, 143, 145, 166, 168, 169, 171, 172, 173, 181, 183, 185, 211, L 42, 43, 45, 48, 49, 86, 90, 92, 93, 95, 97, 111, 113, 114, 115, 116, 118, 120, 121, 124, 126, 128, 130, 132, 134, 135, 157, 158, 159, 160, 161, 164, 171, 173, 175, 177, 204, 210,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
H	No mutation	No mutation	ASP(97)ILE, GLY(99)PHE, TYR(100)ASP, PHE(102)ALA, -(105)ILE, -(107)ASP, SER(129)CYS, LYS(131)ARG,	GLN(3)-, LYS(17)ARG, ARG(29)SER, MET(32)LEU,
L	THR(41)GLN, SER(42)ALA,	GLN(33)ALA,	SER(42)ALA, ARG(45)PRO, SER(92)GLY, TYR(93)ALA, -(160)GLN,	SER(4)LEU, ILE(10)THR, MET(11)LEU, ALA(13)LEU, LYS(18)ARG, VAL(19)ALA, MET(21)LEU, THR(22)SER, SER(24)ARG, SER(28)VAL, ARG(29)GLY, MET(32)LEU, GLN(33)ALA,

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

H:1MIM

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	1MIM.ali
atm file:	1MIM.atm
cof file:	1MIM.cof
hbd file:	1MIM.hbd
html file:	1MIM.html
pdb file:	1MIM.pdb
ps file:	1MIM.ps
psa file:	1MIM.psa
rtf file:	1MIM.rtf
sst file:	1MIM.sst
tem file:	1MIM.tem