Pfam Domains mapped on to the structure: 1MG5

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF00106	short chain dehydrogenase	PF00106	PF00106
2	A	PF08659	KR domain	PF08659	PF08659

Conserved Domain Database Superfamily Annotations: 1MG5

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	1MG5	187584	cd05323	ADH_SDR_c_like -	cl09931
2	1MG5	212616	cl09931	NADB_Rossmann	superfamily - -

Structural Details of PDB entry 1MG5 PDBid Chains Hinge Swapped Domain 1MG5 A,B A:238-250,B:238-250 A:251-255,B:251-255 Swapped-domain interface residues and interactions: Chains Residues A 140, 143, 144, 146, 210, 251, 253, 254, 255, B 140, 143, 144, 146, 206, 207, 210, 251, 253, 254, Non-swapped-domain interface residues and interactions: Chains Residues A 101, 102, 105, 109, 110, 113, 114, 117, 120, 126, 145, 147, 148, 150, 151, 154, 155, 157, 158, 161, 162, 165, 166, 168, 169, 172, 173, 184, 196, 197, 198, 199, 206, 207, 236, 238, 245, 246, 247, 248, 250, B 101, 102, 105, 109, 110, 113, 114, 117, 120, 126, 145, 147, 148, 150, 151, 154, 157, 158, 161, 162, 165, 166, 168, 169, 172, 173, 184, 196, 197, 198, 199, 236, 238, 245, 247, 248, 250,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:1MG5

B:1MG5

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	1MG5.ali
atm file:	1MG5.atm
cof file:	1MG5.cof
hbd file:	1MG5.hbd
html file:	1MG5.html
pdb file:	1MG5.pdb
ps file:	1MG5.ps
psa file:	1MG5.psa
rtf file:	1MG5.rtf
sst file:	1MG5.sst
tem file:	1MG5.tem