Pfam Domains mapped on to the structure: 1LQS

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	R	PF01108	Tissue factor	PF01108	PF01108
2	L	PF00726	Interleukin 10	PF00726	PF00726

Conserved Domain Database Superfamily Annotations: 1LQS

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	1LQS	141468	cl02501	IL10	superfamily - -

Structural Details of PDB entry 1LQS PDBid Chains Hinge Swapped Domain 1LQS M,L M:108-119,L:108-119 M:120-157,L:120-157 Swapped-domain interface residues and interactions: Chains Residues L 16, 23, 27, 37, 38, 42, 47, 48, 56, 64, 76, 79, 80, 120, 121, 123, 124, 125, 127, 128, 129, 131, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150, 151, 152, 153, 154, 155, 157, M 16, 23, 27, 37, 38, 48, 56, 64, 76, 79, 80, 111, 120, 121, 123, 124, 125, 127, 128, 131, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150, 151, 152, 153, 154, 155, Non-swapped-domain interface residues and interactions: Chains Residues L 19, 26, 30, 41, 43, 45, 46, 49, 50, 52, 57, 59, 60, 62, 63, 65, 67, 68, 69, 71, 72, 77, 83, 84, 91, 94, 98, 101, 105, 110, 111, 112, 116, 117, M 19, 26, 30, 34, 41, 43, 45, 46, 47, 49, 50, 52, 57, 59, 60, 62, 63, 65, 67, 68, 69, 71, 72, 77, 83, 84, 91, 94, 98, 101, 105, 110, 112, 114, 116, 117,

Swapped domains are represented using trasperent spheres. Non-swapped part is reprented using light color and cartoon reprentation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
M	No mutation	No mutation	No mutation	No mutation
L	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

M:1LQS

3:1LQS

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	1LQS.ali
atm file:	1LQS.atm
cof file:	1LQS.cof
hbd file:	1LQS.hbd
html file:	1LQS.html
pdb file:	1LQS.pdb
ps file:	1LQS.ps
psa file:	1LQS.psa
rtf file:	1LQS.rtf
sst file:	1LQS.sst
tem file:	1LQS.tem