3DSwap | Knowledgebase of 3D Domain Swapping in Proteins

Pfam Domains mapped on to the structure: 1LGQ

No. Chain ID Pfam ID Pfam Description Linkout - Pfam Linkout - CDD

1 A PF00498 FHA domain PF00498 PF00498

Gene Ontology Annotations: 1LGQ

No. GO ID GO Description Linkout - AmiGO

1 GO:0005515 protein binding GO:0005515

Conserved Domain Database Superfamily Annotations: 1LGQ

No. PDB ID PSSM ID CDD Accession Superfamily Short Name Linkout - CDD

1 1LGQ 28942 cd00060 FHA - cl00062

2 1LGQ 206810 cl00062 FHA superfamily - -

Structural Details of PDB entry 1LGQ

Structural Details of PDB entry 1LGQ

PDBid Chains Hinge Swapped Domain

1LGQ A,B A:85-88,B:85-88 A:89-124,B:89-124

Swapped-domain interface residues and interactions:

Chains Residues
A 15, 16, 17, 18, 19, 20, 21, 22, 55, 56, 72, 73, 74, 75, 76, 77, 78, 80, 81, 82, 83, 84, 85, 86, 87, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 100, 101, 102, 103, 104, 105, 106, 107, 108, 116, 117, 118, 119, 120, 121, 122, 123, 124,

B 16, 17, 18, 19, 20, 21, 22, 55, 56, 72, 73, 74, 75, 76, 77, 78, 80, 81, 82, 83, 84, 85, 86, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 100, 101, 102, 103, 104, 105, 106, 107, 108, 114, 116, 117, 118, 119, 120, 121, 122, 123,

Non-swapped-domain interface residues and interactions:

Chains Residues
A 31, 40, 48, 50, 53, 60, 63, 88,

B 15, 31, 40, 48, 50, 53, 60, 61, 63, 79, 87, 88,

Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.

Mutations in critical regions:

Chains Hinge Domain swapped interface Non-swapped interface Swapped Domain

A No mutation No mutation No mutation No mutation

B No mutation No mutation No mutation No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:1LGQ B:1LGQ

JOY Structural annotation for hinge hinge and swapped domain:

Hinge Swapped domain

JOY output:

ali file: 1LGQ.ali
atm file: 1LGQ.atm
cof file: 1LGQ.cof
hbd file: 1LGQ.hbd
html file: 1LGQ.html
pdb file: 1LGQ.pdb
ps file: 1LGQ.ps
psa file: 1LGQ.psa
rtf file: 1LGQ.rtf
sst file: 1LGQ.sst
tem file: 1LGQ.tem