3DSwap | Knowledgebase of 3D Domain Swapping in Proteins

Pfam Domains mapped on to the structure: 1KN0

No. Chain ID Pfam ID Pfam Description Linkout - Pfam Linkout - CDD

1 A PF04098 Rad52/22 family double-strand break repair protein PF04098 PF04098

Gene Ontology Annotations: 1KN0

No. GO ID GO Description Linkout - AmiGO

1 GO:0006310 DNA recombination GO:0006310

Conserved Domain Database Superfamily Annotations: 1KN0

No. PDB ID PSSM ID CDD Accession Superfamily Short Name Linkout - CDD

1 1KN0 154662 cl01936 Rad52_Rad22 superfamily - -

Structural Details of PDB entry 1KN0

Structural Details of PDB entry 1KN0

PDBid Chains Hinge Swapped Domain

1KN0 F,A,J,K,E,B,H,C,D,I,G F:177-198,A:177-198,J:177-198,K:177-198,E:177-198,B:177-198,H:177-198,C:177-198,D:177-198,I:177-198,G:177-198 F:199-208,A:199-208,J:199-208,K:199-208,E:199-208,B:199-208,H:199-208,C:199-208,D:199-208,I:199-208,G:199-208

Swapped-domain interface residues and interactions:

Chains Residues
A 32, 33, 34, 35, 37, 38, 39, 78, 199, 200, 201, 203, 204, 205, 206, 207, 208,

B 32, 33, 34, 35, 37, 38, 39, 78, 199, 200, 201, 203, 204, 205, 206, 207, 208,

C 32, 33, 34, 35, 37, 38, 39, 199, 200, 201, 203, 204, 205, 206, 207, 208,

D 32, 33, 34, 35, 37, 38, 39, 78, 199, 200, 201, 203, 204, 205, 206, 207, 208,

E 32, 33, 34, 35, 37, 38, 39, 199, 200, 201, 203, 204, 205, 206, 207, 208,

F 32, 33, 34, 35, 37, 38, 39, 78, 199, 200, 201, 203, 204, 205, 206, 207, 208,

G 32, 33, 34, 35, 37, 38, 39, 78, 199, 200, 201, 203, 204, 205, 206, 207,

H 32, 33, 34, 35, 37, 38, 39, 199, 200, 201, 203, 204, 205, 206, 207, 208,

I 32, 33, 34, 35, 37, 38, 39, 199, 200, 201, 203, 204, 205, 206, 207, 208,

J 32, 33, 34, 35, 37, 38, 39, 199, 200, 201, 203, 204, 205, 206, 207, 208,

K 32, 33, 34, 35, 38, 39, 199, 200, 201, 203, 204, 205, 206, 207, 208,

Non-swapped-domain interface residues and interactions:

Chains Residues
A 25, 26, 27, 28, 29, 30, 31, 36, 40, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 67, 69, 70, 72, 73, 74, 76, 77, 80, 81, 82, 84, 85, 86, 87, 88, 91, 94, 95, 97, 108, 110, 112, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 126, 128, 130, 134, 135, 136, 137, 139, 140, 143, 144, 147, 148, 149, 153, 157, 158, 159, 160, 161, 164, 167, 168, 169, 170, 171, 173, 174, 177, 178, 183, 184, 185, 186, 188, 190, 191, 192, 193, 195, 196, 197,

B 25, 26, 27, 28, 29, 30, 31, 36, 40, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 58, 67, 69, 70, 72, 73, 74, 76, 77, 80, 81, 82, 84, 85, 86, 87, 88, 91, 94, 95, 97, 108, 110, 112, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 126, 128, 130, 134, 135, 136, 137, 139, 140, 143, 144, 147, 148, 149, 153, 157, 158, 159, 160, 161, 164, 167, 168, 169, 170, 171, 173, 174, 177, 178, 183, 184, 185, 186, 188, 190, 191, 192, 193, 195, 196, 197,

C 25, 26, 27, 28, 29, 30, 31, 36, 40, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 58, 67, 69, 70, 72, 73, 74, 76, 77, 78, 80, 81, 82, 84, 85, 86, 87, 88, 91, 94, 95, 97, 108, 110, 112, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 126, 128, 130, 134, 135, 136, 137, 139, 140, 143, 144, 147, 148, 149, 153, 157, 158, 159, 160, 161, 164, 167, 168, 169, 170, 171, 173, 174, 178, 183, 184, 185, 186, 188, 190, 191, 192, 193, 195, 196, 197,

D 25, 26, 27, 28, 29, 30, 31, 36, 40, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 58, 67, 69, 70, 72, 73, 74, 76, 77, 79, 80, 81, 82, 84, 85, 86, 87, 88, 91, 94, 95, 97, 108, 110, 112, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 126, 128, 130, 134, 135, 136, 137, 139, 140, 143, 144, 147, 148, 149, 153, 157, 158, 159, 160, 161, 164, 167, 168, 169, 170, 171, 173, 174, 177, 178, 183, 184, 185, 186, 188, 190, 191, 192, 193, 195, 196, 197,

E 25, 26, 27, 28, 29, 30, 31, 36, 40, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 67, 69, 70, 72, 73, 74, 76, 77, 78, 80, 81, 82, 84, 85, 86, 87, 88, 91, 94, 95, 97, 108, 110, 112, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 126, 128, 130, 134, 135, 136, 137, 139, 140, 143, 144, 147, 148, 149, 153, 157, 158, 159, 160, 161, 164, 167, 168, 169, 170, 171, 173, 174, 177, 178, 183, 184, 185, 186, 188, 190, 191, 192, 193, 195, 196, 197,

F 25, 26, 27, 28, 29, 30, 31, 36, 40, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 58, 67, 69, 70, 72, 73, 74, 76, 77, 80, 81, 82, 84, 85, 86, 87, 88, 91, 94, 95, 97, 108, 110, 112, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 126, 128, 130, 134, 135, 136, 137, 139, 140, 143, 144, 147, 148, 149, 153, 157, 158, 159, 160, 161, 164, 167, 168, 169, 170, 171, 173, 174, 177, 178, 183, 184, 185, 186, 188, 190, 191, 192, 193, 195, 196, 197,

G 25, 26, 27, 28, 29, 30, 31, 36, 40, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 58, 67, 69, 70, 72, 73, 74, 76, 77, 80, 81, 82, 84, 85, 86, 87, 88, 91, 94, 95, 97, 108, 110, 112, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 126, 128, 130, 134, 135, 136, 137, 139, 140, 143, 144, 147, 148, 149, 153, 157, 158, 159, 160, 161, 164, 167, 168, 169, 170, 171, 173, 174, 177, 178, 183, 184, 185, 186, 188, 190, 191, 192, 193, 195, 196, 197,

H 25, 26, 27, 28, 29, 30, 31, 36, 40, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 58, 67, 69, 70, 72, 73, 74, 76, 77, 78, 80, 81, 82, 84, 85, 86, 87, 88, 91, 94, 95, 97, 108, 110, 112, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 126, 128, 130, 134, 135, 136, 137, 139, 140, 143, 144, 147, 148, 149, 153, 157, 158, 159, 160, 161, 164, 167, 168, 169, 170, 171, 173, 174, 177, 178, 183, 184, 185, 186, 188, 190, 191, 192, 193, 195, 196, 197,

I 25, 26, 27, 28, 29, 30, 31, 36, 40, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 58, 67, 69, 70, 72, 73, 74, 76, 77, 78, 80, 81, 82, 84, 85, 86, 87, 88, 91, 94, 95, 97, 108, 110, 112, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 126, 128, 130, 134, 135, 136, 137, 139, 140, 143, 144, 147, 148, 149, 153, 157, 158, 159, 160, 161, 164, 167, 168, 169, 170, 171, 173, 174, 178, 183, 184, 185, 186, 188, 190, 191, 192, 193, 195, 196, 197,

J 25, 26, 27, 28, 29, 30, 31, 36, 40, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 58, 67, 69, 70, 72, 73, 74, 76, 77, 78, 80, 81, 82, 84, 85, 86, 87, 88, 91, 94, 95, 97, 108, 110, 112, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 126, 128, 130, 134, 135, 136, 137, 139, 140, 143, 144, 147, 148, 149, 153, 157, 158, 159, 160, 161, 164, 167, 168, 169, 170, 171, 173, 174, 177, 178, 183, 184, 185, 186, 188, 190, 191, 192, 193, 195, 196, 197,

K 25, 26, 27, 28, 29, 30, 31, 36, 37, 40, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 58, 67, 69, 70, 72, 73, 74, 76, 77, 78, 80, 81, 82, 84, 85, 86, 87, 88, 91, 94, 95, 97, 108, 110, 112, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 126, 128, 130, 134, 135, 136, 137, 139, 140, 143, 144, 147, 148, 149, 153, 157, 158, 159, 160, 161, 164, 167, 168, 169, 170, 171, 173, 174, 177, 178, 183, 184, 185, 186, 188, 190, 191, 192, 193, 195, 196, 197,

Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.

Mutations in critical regions:

Chains Hinge Domain swapped interface Non-swapped interface Swapped Domain

F No mutation No mutation No mutation No mutation

A No mutation No mutation No mutation No mutation

J No mutation No mutation No mutation No mutation

K No mutation No mutation No mutation No mutation

E No mutation No mutation No mutation No mutation

B No mutation No mutation No mutation No mutation

H No mutation No mutation No mutation No mutation

C No mutation No mutation No mutation No mutation

D No mutation No mutation No mutation No mutation

I No mutation No mutation No mutation No mutation

G No mutation No mutation No mutation No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

F:1KN0 G:1KN0

JOY Structural annotation for hinge hinge and swapped domain:

Hinge Swapped domain

JOY output:

ali file: 1KN0.ali
atm file: 1KN0.atm
pdb file: 1KN0.pdb
psa file: 1KN0.psa
sst file: 1KN0.sst