Pfam Domains mapped on to the structure: 1KH3

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF00764	Arginosuccinate synthase	PF00764	PF00764

Conserved Domain Database Superfamily Annotations: 1KH3

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	1KH3	30186	cd01999	Argininosuccinate_Synthase -	cl00292
2	1KH3	206963	cl00292	AANH_like	superfamily - -
3	1KH3	206963	cl00292	AANH_like	superfamily - -

Structural Details of PDB entry 1KH3 PDBid Chains Hinge Swapped Domain 1KH3 A,B A:349-373,B:349-373 A:374-395,B:374-395 Swapped-domain interface residues and interactions: Chains Residues A 117, 123, 127, 130, 131, 134, 143, 316, 374, 375, 376, 377, 378, 379, 380, 381, 382, 383, 384, 385, 386, 387, 388, 389, 390, 391, 392, 393, 394, 395, B 117, 123, 127, 130, 131, 134, 143, 316, 374, 375, 376, 377, 378, 379, 380, 381, 382, 383, 384, 385, 386, 387, 388, 389, 390, 391, 392, 393, 394, 395, C 262, 263, 264, 355, 357, 370, 375, 376, 377, 378, 379, 381, 382, D 262, 263, 264, 355, 357, 370, 371, 374, 375, 376, 377, 378, 379, 381, 382, Non-swapped-domain interface residues and interactions: Chains Residues A 81, 82, 83, 116, 118, 122, 126, 142, 189, 191, 192, 194, 206, 207, 213, 215, 217, 253, 255, 257, 259, 260, 261, 262, 263, 264, 265, 266, 267, 280, 283, 287, 288, 290, 291, 292, 293, 294, 295, 296, 297, 299, 300, 301, 303, 304, 307, 311, 313, 317, 318, 320, 321, 322, 324, 325, 328, 338, 340, 342, 343, 344, 345, 347, 348, 349, 350, 351, 352, 355, 356, 357, 358, 359, 370, 371, 373, B 81, 82, 83, 118, 122, 126, 135, 189, 191, 192, 194, 206, 207, 213, 215, 217, 253, 255, 257, 259, 261, 262, 263, 264, 265, 266, 267, 280, 283, 287, 288, 290, 291, 292, 293, 294, 295, 296, 297, 299, 300, 301, 303, 304, 307, 311, 313, 317, 318, 320, 321, 322, 324, 325, 328, 338, 340, 342, 343, 344, 345, 347, 348, 349, 350, 351, 352, 355, 356, 357, 358, 359, 360, 362, 363, 364, 365, 370, 371, 373, C 81, 82, 83, 116, 117, 118, 122, 123, 126, 127, 130, 131, 134, 135, 142, 143, 149, 189, 191, 192, 194, 206, 207, 213, 215, 217, 253, 255, 257, 259, 260, 261, 265, 266, 267, 280, 283, 287, 288, 290, 291, 292, 293, 294, 295, 296, 297, 299, 300, 301, 303, 304, 307, 311, 313, 316, 317, 318, 320, 321, 322, 324, 325, 328, 338, 340, 342, 343, 344, 345, 347, 348, 349, 350, 351, 352, 356, 358, 359, 360, 362, 363, 364, 365, 371, 373, 374, 380, 383, 384, 385, 386, 387, 388, 389, 390, 391, 392, 393, 394, 395, D 81, 82, 83, 116, 117, 118, 122, 123, 126, 127, 130, 131, 134, 142, 143, 144, 189, 191, 192, 194, 206, 207, 213, 215, 217, 253, 255, 257, 259, 260, 261, 265, 266, 267, 280, 283, 287, 288, 290, 291, 292, 293, 294, 295, 296, 297, 299, 300, 301, 303, 304, 307, 311, 313, 316, 317, 318, 320, 321, 322, 324, 325, 328, 338, 340, 342, 343, 344, 345, 347, 348, 349, 350, 351, 352, 356, 358, 359, 360, 362, 363, 364, 365, 373, 380, 383, 384, 385, 386, 387, 388, 389, 390, 391, 392, 393, 394,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:1KH3

D:1KH3

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	1KH3.ali
atm file:	1KH3.atm
cof file:	1KH3.cof
hbd file:	1KH3.hbd
html file:	1KH3.html
pdb file:	1KH3.pdb
ps file:	1KH3.ps
psa file:	1KH3.psa
rtf file:	1KH3.rtf
sst file:	1KH3.sst
tem file:	1KH3.tem