Pfam Domains mapped on to the structure: 1KAH

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF00815	Histidinol dehydrogenase	PF00815	PF00815

Conserved Domain Database Superfamily Annotations: 1KAH

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	1KAH	119329	cd06572	Histidinol_dh -	cl10029
2	1KAH	199949	cl10029	Histidinol_dh	superfamily - -
3	1KAH	199949	cl10029	Histidinol_dh	superfamily - -

Structural Details of PDB entry 1KAH PDBid Chains Hinge Swapped Domain 1KAH A,B A:102-103,B:102-103 A:387-434,B:387-434 Swapped-domain interface residues and interactions: Chains Residues A 84, 87, 136, 137, 138, 251, 254, 258, 261, 292, 346, 347, 348, 349, 350, 351, 353, 354, 355, 357, 358, 361, 362, 377, 379, 380, 388, 389, 391, 392, 393, 394, 395, 397, 400, 403, 406, 407, 409, 410, 411, 413, 414, 415, 416, 417, 418, 419, 421, 422, 423, 425, 426, 429, 430, 434, B 84, 87, 136, 137, 138, 251, 254, 258, 292, 346, 347, 348, 349, 350, 351, 353, 354, 355, 357, 358, 361, 362, 377, 378, 379, 380, 388, 389, 391, 392, 393, 394, 395, 397, 400, 403, 406, 407, 409, 410, 411, 413, 414, 415, 416, 417, 418, 419, 421, 422, 423, 425, 426, 429, 430, Non-swapped-domain interface residues and interactions: Chains Residues A 26, 83, 90, 91, 94, 97, 98, 101, 102, 104, 105, 107, 109, 111, 112, 115, 116, 117, 118, 119, 122, 124, 135, 139, 204, 205, 219, 223, 225, 229, 250, 262, 288, 293, 294, 336, 339, 340, 342, 343, 352, 363, 365, 372, 374, 375, 376, 382, 384, 385, B 25, 26, 83, 90, 91, 93, 94, 97, 98, 101, 102, 104, 105, 107, 109, 111, 112, 115, 116, 117, 118, 119, 122, 124, 135, 139, 204, 205, 219, 223, 225, 229, 250, 261, 262, 288, 293, 294, 336, 339, 340, 342, 343, 344, 352, 363, 365, 372, 374, 375, 376, 382, 384, 385,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	LEU(403)VAL,	No mutation	LEU(403)VAL,
B	No mutation	LEU(403)VAL,	No mutation	LEU(403)VAL,

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

B:1KAH

A:1KAH

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	1KAH.ali
atm file:	1KAH.atm
cof file:	1KAH.cof
hbd file:	1KAH.hbd
html file:	1KAH.html
pdb file:	1KAH.pdb
ps file:	1KAH.ps
psa file:	1KAH.psa
rtf file:	1KAH.rtf
sst file:	1KAH.sst
tem file:	1KAH.tem