3DSwap | Knowledgebase of 3D Domain Swapping in Proteins

Pfam Domains mapped on to the structure: 1K94

No. Chain ID Pfam ID Pfam Description Linkout - Pfam Linkout - CDD

1 A PF13833 EF-hand domain pair PF13833 PF13833

2 A PF13405 EF-hand domain PF13405 PF13405

3 A PF13202 EF hand PF13202 PF13202

Conserved Domain Database Superfamily Annotations: 1K94

No. PDB ID PSSM ID CDD Accession Superfamily Short Name Linkout - CDD

1 1K94 28933 cd00051 EFh - cl08302

2 1K94 208857 cl08302 EFh superfamily - -

3 1K94 28933 cd00051 EFh - cl08302

4 1K94 208857 cl08302 EFh superfamily - -

5 1K94 28933 cd00051 EFh - cl08302

6 1K94 208857 cl08302 EFh superfamily - -

7 1K94 208857 cl08302 EFh superfamily - -

8 1K94 208857 cl08302 EFh superfamily - -

Structural Details of PDB entry 1K94

Structural Details of PDB entry 1K94

PDBid Chains Hinge Swapped Domain

1K94 A,B A:15-19,B:15-19 A:3-15,B:3-15

Swapped-domain interface residues and interactions:

Chains Residues

Non-swapped-domain interface residues and interactions:

Chains Residues
A 92, 95, 105, 153, 154, 155, 156, 158, 159, 161, 162, 163, 165, 166, 167, 169, 170, 177, 184, 185, 188, 189, 192, 201, 202, 203, 204, 205, 206, 207, 208, 210, 211, 212, 214, 215, 216, 217,

B 369, 391, 392, 395, 399, 405, 406, 407, 454, 455, 456, 458, 459, 462, 463, 465, 466, 484, 485, 488, 489, 492, 501, 502, 503, 504, 505, 506, 507, 508, 510, 511, 512, 514, 515, 516,

Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.

Mutations in critical regions:

Chains Hinge Domain swapped interface Non-swapped interface Swapped Domain

A No mutation No mutation No mutation No mutation

B No mutation No mutation No mutation No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:1K94 B:1K94

JOY Structural annotation for hinge hinge and swapped domain:

Hinge Swapped domain

JOY output:

ali file: 1K94.ali
atm file: 1K94.atm
cof file: 1K94.cof
hbd file: 1K94.hbd
html file: 1K94.html
pdb file: 1K94.pdb
ps file: 1K94.ps
psa file: 1K94.psa
rtf file: 1K94.rtf
sst file: 1K94.sst
tem file: 1K94.tem