Pfam Domains mapped on to the structure: 1JPY

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF06083	Interleukin-17	PF06083	PF06083

Gene Ontology Annotations: 1JPY

No.	GO ID	GO Description	Linkout - AmiGO
1	GO:0005576	extracellular region	GO:0005576

Conserved Domain Database Superfamily Annotations: 1JPY

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	1JPY	191444	cl05558	IL17	superfamily - -

Structural Details of PDB entry 1JPY PDBid Chains Hinge Swapped Domain 1JPY A,D,C,B A:39-42,D:39-42,C:39-42,B:39-42 A:8-38,D:8-38,C:8-38,B:8-38 Swapped-domain interface residues and interactions: Chains Residues A 8, 9, 10, 11, 12, 13, 14, 17, 18, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 36, 37, 38, 94, 95, 96, 106, 107, 110, 111, 112, 113, 114, 115, 117, B 8, 10, 11, 12, 13, 14, 17, 18, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 36, 37, 38, 94, 95, 96, 107, 109, 110, 111, 112, 113, 114, 115, 117, X 56, 58, Non-swapped-domain interface residues and interactions: Chains Residues A 39, 40, 41, 44, 47, 48, 49, 52, 60, 63, 64, 88, 91, 92, 93, 97, 98, 100, 101, 102, 103, 109, 118, 120, 121, 122, 123, 124, 125, 126, B 39, 40, 41, 42, 44, 45, 47, 48, 49, 54, 55, 56, 57, 58, 60, 63, 64, 65, 66, 68, 69, 88, 91, 92, 93, 97, 98, 100, 101, 102, 103, 106, 118, 120, 122, 123, 124, 125, 126, 128, X 10, 11, 12, 13, 14, 17, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 43, 44, 46, 47, 48, 49, 52, 55, 60, 62, 63, 64, 65, 66, 68, 73, 78, 80, 82, 88, 91, 92, 93, 94, 95, 96, 97, 98, 100, 101, 102, 103, 106, 107, 109, 110, 111, 112, 113, 114, 115, 117, 118, 120, 121, 122, 123, 124, 125, 126, 128, Y 6, 7, 8, 9, 10, 11, 12, 13, 14, 17, 18, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 36, 37, 38, 39, 40, 41, 44, 47, 48, 49, 60, 63, 64, 80, 88, 91, 92, 93, 94, 95, 96, 97, 98, 100, 101, 102, 103, 106, 107, 109, 110, 111, 112, 113, 114, 115, 117, 118, 120, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	No mutation	No mutation	No mutation
D	No mutation	No mutation	No mutation	No mutation
C	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

B:1JPY

C:1JPY

D:1JPY

A:1JPY

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	1JPY.ali
atm file:	1JPY.atm
cof file:	1JPY.cof
hbd file:	1JPY.hbd
html file:	1JPY.html
pdb file:	1JPY.pdb
ps file:	1JPY.ps
psa file:	1JPY.psa
rtf file:	1JPY.rtf
sst file:	1JPY.sst
tem file:	1JPY.tem