3DSwap | Knowledgebase of 3D Domain Swapping in Proteins

Pfam Domains mapped on to the structure: 1JFQ

No. Chain ID Pfam ID Pfam Description Linkout - Pfam Linkout - CDD

1 L PF13895 Immunoglobulin domain PF13895 PF13895

2 L PF00047 Immunoglobulin domain PF00047 PF00047

3 H PF13895 Immunoglobulin domain PF13895 PF13895

Conserved Domain Database Superfamily Annotations: 1JFQ

No. PDB ID PSSM ID CDD Accession Superfamily Short Name Linkout - CDD

1 1JFQ 143182 cd04981 IgV_H - cl11960

2 1JFQ 212623 cl11960 Ig superfamily - -

3 1JFQ 143186 cd04985 IgC_CH1 - cl11960

4 1JFQ 212623 cl11960 Ig superfamily - -

5 1JFQ 212623 cl11960 Ig superfamily - -

Structural Details of PDB entry 1JFQ

Structural Details of PDB entry 1JFQ

PDBid Chains Hinge Swapped Domain

1JFQ H,L H:342-345,L:41-44 H:302-341,L:1-40

Swapped-domain interface residues and interactions:

Chains Residues
H 339, 405, 407,

L 32, 34, 36, 38,

Non-swapped-domain interface residues and interactions:

Chains Residues
H 343, 344, 345, 347, 359, 361, 395, 402, 403, 404, 406, 408, 409, 411, 413, 430, 431, 432, 433, 435, 436, 437, 439, 440, 445, 447, 449, 451, 472, 473, 474, 475, 477, 479, 484, 486, 488, 516,

L 42, 43, 44, 46, 49, 50, 55, 85, 87, 89, 91, 94, 95, 96, 98, 100, 101, 114, 116, 117, 118, 119, 120, 121, 123, 124, 127, 131, 133, 135, 137, 138, 160, 161, 162, 163, 164, 174, 176, 178, 180, 209, 213, 214, 215,

Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.

Mutations in critical regions:

Chains Hinge Domain swapped interface Non-swapped interface Swapped Domain

H No mutation No mutation No mutation No mutation

L No mutation No mutation No mutation No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

H:1JFQ

JOY Structural annotation for hinge hinge and swapped domain:

Hinge Swapped domain

JOY output:

ali file: 1JFQ.ali
atm file: 1JFQ.atm
cof file: 1JFQ.cof
hbd file: 1JFQ.hbd
html file: 1JFQ.html
pdb file: 1JFQ.pdb
ps file: 1JFQ.ps
psa file: 1JFQ.psa
rtf file: 1JFQ.rtf
sst file: 1JFQ.sst
tem file: 1JFQ.tem