Pfam Domains mapped on to the structure: 1IZC

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF03328	HpcH/HpaI aldolase/citrate lyase family	PF03328	PF03328

Conserved Domain Database Superfamily Annotations: 1IZC

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	1IZC	208991	cl09155	Pyruvate_Kinase	superfamily - -
2	1IZC	208991	cl09155	Pyruvate_Kinase	superfamily - -

Structural Details of PDB entry 1IZC PDBid Chains Hinge Swapped Domain 1IZC A,B A:273-276,B:273-276 A:277-300,B:277-300 Swapped-domain interface residues and interactions: Chains Residues A 277, 279, 280, 281, 283, 284, 285, 287, 288, 290, 291, 292, 294, 295, 296, 297, 298, 299, 300, E 38, 39, 40, 44, 58, 59, 62, 64, 257, 260, 261, 273, 274, 280, Non-swapped-domain interface residues and interactions: Chains Residues A 37, 38, 39, 40, 44, 46, 49, 50, 51, 52, 54, 55, 58, 59, 62, 63, 64, 65, 75, 95, 257, 260, 261, 264, 265, 273, 274, 276, E 37, 46, 49, 50, 51, 52, 54, 55, 63, 65, 75, 95, 264, 265, 276, 277, 279, 281, 283, 284, 285, 287, 288, 290, 291, 292, 294, 295, 296, 297, 298, 299,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:1IZC

E:1IZC

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	1IZC.ali
atm file:	1IZC.atm
cof file:	1IZC.cof
hbd file:	1IZC.hbd
html file:	1IZC.html
pdb file:	1IZC.pdb
ps file:	1IZC.ps
psa file:	1IZC.psa
rtf file:	1IZC.rtf
sst file:	1IZC.sst
tem file:	1IZC.tem