Pfam Domains mapped on to the structure: 1IXX
Conserved Domain Database Superfamily Annotations: 1IXX
Structural Details of PDB entry 1IXX
Structural Details of PDB entry 1IXX
PDBid
Chains
Hinge
Swapped Domain
1IXX
F,A,D,C,E,B
F:72-75,A:75-78,D:72-75,C:72-75,E:72-75,B:75-78;A:95-100,B:95-100
F:76-92,A:79-94,D:76-92,C:76-92,E:76-92,B:79-94
Swapped-domain interface residues and interactions:
Chains
Residues
A
38 , 41 , 43 , 44 , 69 , 70 , 71 , 79 , 80 , 83 , 84 , 85 , 87 , 89 , 90 , 91 , 92 , 93 , 94 , 113 , 114 , 115 ,
B
38 , 41 , 43 , 44 , 67 , 68 , 70 , 71 , 72 , 74 , 75 , 79 , 80 , 81 , 83 , 84 , 85 , 86 , 87 , 89 , 90 , 91 , 105 , 106 , 107 ,
C
38 , 41 , 43 , 44 , 69 , 70 , 71 , 72 , 73 , 77 , 78 , 79 , 80 , 83 , 84 , 85 , 87 , 89 , 90 , 91 , 92 , 113 , 114 , 115 ,
D
38 , 41 , 43 , 44 , 67 , 68 , 71 , 72 , 74 , 75 , 76 , 77 , 78 , 79 , 80 , 81 , 83 , 84 , 85 , 87 , 89 , 90 , 91 ,
E
38 , 41 , 43 , 44 , 69 , 70 , 71 , 72 , 73 , 77 , 78 , 79 , 80 , 83 , 84 , 85 , 87 , 89 , 91 , 92 , 113 , 114 , 115 ,
F
38 , 41 , 43 , 44 , 67 , 68 , 71 , 72 , 74 , 75 , 76 , 77 , 78 , 79 , 80 , 81 , 83 , 85 , 87 , 89 , 90 , 91 ,
Non-swapped-domain interface residues and interactions:
Chains
Residues
A
27 , 42 , 45 , 48 , 61 , 63 , 64 , 65 , 72 , 73 , 75 , 77 , 78 , 95 , 96 , 98 , 100 , 101 , 103 , 106 , 107 , 108 , 116 , 129 ,
B
20 , 27 , 42 , 45 , 49 , 53 , 56 , 57 , 60 , 61 , 62 , 63 , 69 , 76 , 77 , 78 , 95 , 97 , 102 , 104 , 108 , 109 , 112 , 113 , 114 , 116 , 123 ,
C
27 , 42 , 45 , 48 , 60 , 61 , 63 , 64 , 75 , 93 , 94 , 95 , 96 , 98 , 100 , 101 , 103 , 106 , 107 , 108 , 109 , 116 , 129 ,
D
20 , 27 , 42 , 45 , 49 , 53 , 56 , 57 , 60 , 61 , 62 , 63 , 69 , 95 , 97 , 100 , 102 , 103 , 104 , 105 , 106 , 107 , 108 , 109 , 112 , 113 , 114 , 116 , 123 ,
E
42 , 45 , 48 , 61 , 63 , 64 , 75 , 93 , 94 , 95 , 96 , 98 , 100 , 101 , 103 , 106 , 107 , 108 , 109 , 116 , 118 ,
F
19 , 20 , 27 , 42 , 45 , 49 , 53 , 56 , 57 , 60 , 61 , 62 , 63 , 69 , 95 , 97 , 102 , 103 , 104 , 105 , 106 , 107 , 108 , 109 , 112 , 113 , 114 , 116 , 123 ,
Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.
Mutations in critical regions:
Chains
Hinge
Domain swapped interface
Non-swapped interface
Swapped Domain
F No mutation No mutation No mutation No mutation
A No mutation No mutation No mutation No mutation
D No mutation No mutation No mutation No mutation
C No mutation No mutation No mutation No mutation
E No mutation No mutation No mutation No mutation
B No mutation No mutation No mutation No mutation
B No mutation No mutation No mutation No mutation
HIDE output:
JMOL Visualization:
2D-plot:
JOY Structural annotation for hinge hinge and swapped domain:
JOY output: