3DSwap | Knowledgebase of 3D Domain Swapping in Proteins

Pfam Domains mapped on to the structure: 1IOM

No. Chain ID Pfam ID Pfam Description Linkout - Pfam Linkout - CDD

1 A PF00285 Citrate synthase PF00285 PF00285

Conserved Domain Database Superfamily Annotations: 1IOM

No. PDB ID PSSM ID CDD Accession Superfamily Short Name Linkout - CDD

1 1IOM 99871 cd06118 citrate_synt_like_1 - cl00416

2 1IOM 199305 cl00416 CS_ACL-C_CCL superfamily - -

3 1IOM 199305 cl00416 CS_ACL-C_CCL superfamily - -

Structural Details of PDB entry 1IOM

Structural Details of PDB entry 1IOM

PDBid Chains Hinge Swapped Domain

1IOM A,B A:352-364,B:352-364 A:365-376,B:365-376

Swapped-domain interface residues and interactions:

Chains Residues
A 31, 32, 36, 57, 58, 366, 367, 368, 369, 370, 371, 373, 374, 376,

B 31, 32, 36, 57, 58, 366, 367, 368, 369, 370, 371, 373, 374,

Non-swapped-domain interface residues and interactions:

Chains Residues
A 3, 4, 5, 6, 7, 8, 10, 11, 12, 13, 14, 15, 16, 18, 19, 28, 33, 40, 45, 55, 56, 61, 77, 80, 81, 84, 85, 86, 89, 93, 96, 97, 100, 101, 103, 105, 109, 110, 186, 188, 191, 192, 195, 196, 198, 199, 200, 201, 202, 205, 208, 209, 212, 213, 215, 216, 217, 218, 259, 351, 352, 353, 354, 355, 356, 357, 358, 359, 360, 361, 362, 363, 364,

B 3, 4, 5, 6, 7, 8, 10, 11, 12, 13, 14, 15, 16, 18, 19, 28, 33, 40, 45, 55, 56, 61, 77, 80, 81, 84, 85, 86, 89, 93, 96, 97, 100, 101, 103, 105, 109, 110, 186, 188, 191, 192, 195, 196, 198, 199, 200, 201, 202, 205, 208, 209, 212, 213, 215, 216, 217, 218, 259, 351, 352, 353, 354, 355, 356, 357, 358, 359, 360, 361, 362, 363, 364,

Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.

Mutations in critical regions:

Chains Hinge Domain swapped interface Non-swapped interface Swapped Domain

A No mutation No mutation No mutation No mutation

B No mutation No mutation No mutation No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:1IOM B:1IOM

JOY Structural annotation for hinge hinge and swapped domain:

Hinge Swapped domain

JOY output:

ali file: 1IOM.ali
atm file: 1IOM.atm
cof file: 1IOM.cof
hbd file: 1IOM.hbd
html file: 1IOM.html
pdb file: 1IOM.pdb
ps file: 1IOM.ps
psa file: 1IOM.psa
rtf file: 1IOM.rtf
sst file: 1IOM.sst
tem file: 1IOM.tem