3DSwap | Knowledgebase of 3D Domain Swapping in Proteins

Pfam Domains mapped on to the structure: 1IOD

No. Chain ID Pfam ID Pfam Description Linkout - Pfam Linkout - CDD

1 A PF00059 Lectin C-type domain PF00059 PF00059

2 B PF00059 Lectin C-type domain PF00059 PF00059

3 G PF00594 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain PF00594 PF00594

Gene Ontology Annotations: 1IOD

No. GO ID GO Description Linkout - AmiGO

1 GO:0005576 extracellular region GO:0005576

Conserved Domain Database Superfamily Annotations: 1IOD

No. PDB ID PSSM ID CDD Accession Superfamily Short Name Linkout - CDD

1 1IOD 141428 Gla superfamily N -

Structural Details of PDB entry 1IOD

Structural Details of PDB entry 1IOD

PDBid Chains Hinge Swapped Domain

1IOD A,G,B A:100-101,G:100-101,B:100-101 A:73-101,G:73-101,B:73-101

Swapped-domain interface residues and interactions:

Chains Residues
A 73, 74, 77, 78, 79, 80, 81, 83, 84, 85, 87, 89, 90, 91, 93, 94, 95, 98, 100, 101,

B 238, 241, 242, 243, 244, 267, 268, 271, 272, 274, 275, 276, 277, 305, 306, 307, 308,

Non-swapped-domain interface residues and interactions:

Chains Residues
A 27, 38, 41, 42, 43, 44, 45, 48, 69, 70, 71, 72, 103, 112, 113, 114, 115, 116, 129,

B 227, 245, 248, 269, 270, 278, 279, 280, 281, 283, 284, 285, 287, 289, 290, 291, 295, 297, 304,

Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.

Mutations in critical regions:

Chains Hinge Domain swapped interface Non-swapped interface Swapped Domain

A No mutation No mutation No mutation No mutation

G No mutation No mutation No mutation No mutation

B No mutation No mutation No mutation No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:1IOD B:1IOD G:1IOD

JOY Structural annotation for hinge hinge and swapped domain:

Hinge Swapped domain

JOY output:

ali file: 1IOD.ali
atm file: 1IOD.atm
cof file: 1IOD.cof
hbd file: 1IOD.hbd
html file: 1IOD.html
pdb file: 1IOD.pdb
ps file: 1IOD.ps
psa file: 1IOD.psa
rtf file: 1IOD.rtf
sst file: 1IOD.sst
tem file: 1IOD.tem