Pfam Domains mapped on to the structure: 1IA9
No.
Chain ID
Pfam ID
Pfam Description
Linkout - Pfam
Linkout - CDD
1
A
PF02816
Alpha-kinase family
PF02816
PF02816
Gene Ontology Annotations: 1IA9
Conserved Domain Database Superfamily Annotations: 1IA9
Structural Details of PDB entry 1IA9
Structural Details of PDB entry 1IA9
PDBid
Chains
Hinge
Swapped Domain
1IA9
A,B
A:1574-1577,B:1574-1577
A:1551-1573,B:1549-1573
Swapped-domain interface residues and interactions:
Chains
Residues
A
1551 , 1552 , 1553 , 1556 , 1557 , 1558 , 1560 , 1561 , 1562 , 1563 , 1564 , 1565 , 1567 , 1568 , 1569 , 1570 , 1571 , 1572 , 1573 , 1594 , 1595 , 1596 , 1597 , 1600 , 1602 , 1603 , 1674 , 1678 , 1756 , 1757 , 1758 , 1791 ,
B
1549 , 1550 , 1551 , 1552 , 1553 , 1556 , 1557 , 1558 , 1560 , 1561 , 1562 , 1563 , 1564 , 1565 , 1566 , 1567 , 1568 , 1569 , 1570 , 1571 , 1572 , 1573 , 1594 , 1595 , 1596 , 1597 , 1599 , 1600 , 1602 , 1603 , 1604 , 1674 , 1678 , 1756 , 1757 , 1791 ,
Non-swapped-domain interface residues and interactions:
Chains
Residues
A
1575 , 1576 , 1579 , 1583 , 1598 , 1599 , 1601 , 1604 , 1606 , 1608 , 1630 , 1631 , 1633 , 1660 , 1666 , 1667 , 1670 , 1671 , 1681 , 1682 , 1689 , 1714 , 1752 , 1755 , 1760 , 1761 , 1780 , 1817 , 1820 , 1828 ,
B
1581 , 1583 , 1598 , 1601 , 1606 , 1631 , 1633 , 1634 , 1635 , 1639 , 1666 , 1667 , 1670 , 1671 , 1681 , 1682 , 1689 , 1714 , 1758 , 1760 , 1761 , 1780 ,
Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.
Mutations in critical regions:
Chains
Hinge
Domain swapped interface
Non-swapped interface
Swapped Domain
A No mutation No mutation No mutation No mutation
B No mutation No mutation No mutation No mutation
HIDE output:
JMOL Visualization:
2D-plot:
JOY Structural annotation for hinge hinge and swapped domain:
JOY output: