Pfam Domains mapped on to the structure: 1I4M

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF00377	Prion/Doppel alpha-helical domain	PF00377	PF00377

Conserved Domain Database Superfamily Annotations: 1I4M

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	1I4M	198690	Prion	superfamily	N -

Structural Details of PDB entry 1I4M PDBid Chains Hinge Swapped Domain 1I4M A,B A:189-199,B:189-199 A:200-226,B:200-226 Swapped-domain interface residues and interactions: Chains Residues A 131, 137, 150, 157, 161, 166, 176, 179, 180, 201, 202, 204, 205, 206, 207, 208, 209, 210, 211, 212, 213, 214, 215, 216, 217, 218, 220, 221, 222, 225, 226, B 131, 137, 150, 157, 161, 166, 176, 179, 180, 201, 202, 204, 205, 206, 207, 208, 209, 210, 211, 212, 213, 214, 215, 216, 217, 218, 220, 221, 222, 225, Non-swapped-domain interface residues and interactions: Chains Residues A 132, 133, 134, 139, 141, 145, 146, 148, 149, 153, 156, 158, 163, 167, 172, 175, 184, 187, 188, 189, 190, 191, 192, 193, 194, 195, 197, 198, B 132, 133, 134, 139, 141, 145, 146, 148, 149, 153, 156, 158, 163, 167, 172, 175, 184, 187, 188, 189, 190, 191, 192, 193, 194, 195, 197, 198,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:1I4M

B:1I4M

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	1I4M.ali
atm file:	1I4M.atm
cof file:	1I4M.cof
hbd file:	1I4M.hbd
html file:	1I4M.html
pdb file:	1I4M.pdb
ps file:	1I4M.ps
psa file:	1I4M.psa
rtf file:	1I4M.rtf
sst file:	1I4M.sst
tem file:	1I4M.tem