3DSwap | Knowledgebase of 3D Domain Swapping in Proteins

Pfam Domains mapped on to the structure: 1HW7

No. Chain ID Pfam ID Pfam Description Linkout - Pfam Linkout - CDD

1 A PF01430 Hsp33 protein PF01430 PF01430

Gene Ontology Annotations: 1HW7

No. GO ID GO Description Linkout - AmiGO

1 GO:0005737 cytoplasm GO:0005737

Conserved Domain Database Superfamily Annotations: 1HW7

No. PDB ID PSSM ID CDD Accession Superfamily Short Name Linkout - CDD

1 1HW7 29605 cd00498 Hsp33 - cl00236

2 1HW7 199268 cl00236 Hsp33 superfamily - -

3 1HW7 199268 cl00236 Hsp33 superfamily - -

Structural Details of PDB entry 1HW7

Structural Details of PDB entry 1HW7

PDBid Chains Hinge Swapped Domain

1HW7 A,B A:174-189,B:174-189 A:190-234,B:190-234

Swapped-domain interface residues and interactions:

Chains Residues
A 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 25, 29, 32, 88, 89, 90, 91, 157, 159, 160, 168, 169, 170, 190, 191, 194, 195, 197, 199, 202, 203, 204, 207, 210, 211, 215, 218, 219, 220, 221, 222, 223, 224, 225, 226, 227, 228, 229, 230, 231, 234,

B 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 25, 29, 32, 88, 89, 90, 91, 157, 159, 160, 168, 169, 170, 190, 191, 194, 195, 197, 199, 202, 203, 204, 207, 210, 211, 215, 218, 219, 220, 221, 222, 223, 224, 225, 226, 227, 228, 229, 230, 231,

Non-swapped-domain interface residues and interactions:

Chains Residues
A 17, 18, 19, 23, 33, 60, 62, 63, 85, 87, 119, 121, 124, 125, 126, 127, 128, 129, 130, 131, 132, 134, 144, 147, 148, 149, 150, 151, 152, 153, 155, 161, 163, 171, 172, 174, 175, 176, 178, 179, 180, 181, 182, 184, 186, 187, 188,

B 17, 18, 19, 23, 33, 60, 62, 63, 85, 87, 119, 121, 124, 125, 126, 127, 128, 129, 130, 131, 132, 134, 144, 147, 148, 149, 150, 151, 152, 153, 155, 161, 163, 171, 172, 174, 175, 176, 178, 179, 180, 181, 182, 184, 186, 187, 188,

Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.

Mutations in critical regions:

Chains Hinge Domain swapped interface Non-swapped interface Swapped Domain

A No mutation No mutation No mutation No mutation

B No mutation No mutation No mutation No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:1HW7 B:1HW7

JOY Structural annotation for hinge hinge and swapped domain:

Hinge Swapped domain

JOY output:

ali file: 1HW7.ali
atm file: 1HW7.atm
cof file: 1HW7.cof
hbd file: 1HW7.hbd
html file: 1HW7.html
pdb file: 1HW7.pdb
ps file: 1HW7.ps
psa file: 1HW7.psa
rtf file: 1HW7.rtf
sst file: 1HW7.sst
tem file: 1HW7.tem