Pfam Domains mapped on to the structure: 1HT9

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF01023	S-100/ICaBP type calcium binding domain	PF01023	PF01023
2	A	PF13499	EF-hand domain pair	PF13499	PF13499
3	A	PF00036	EF hand	PF00036	PF00036

Conserved Domain Database Superfamily Annotations: 1HT9

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	1HT9	88292	cd00213	S-100 -	cl08302
2	1HT9	208857	cl08302	EFh	superfamily - -

Structural Details of PDB entry 1HT9 PDBid Chains Hinge Swapped Domain 1HT9 A,B A:38-45,B:38-45 A:46-75,B:46-75 Swapped-domain interface residues and interactions: Chains Residues A 22, 23, 24, 25, 45, 46, 47, 48, 49, 50, 51, 52, 53, 59, 60, 61, 62, 63, 66, 69, 70, 72, 73, 74, 75, B 1, 3, 6, 22, 23, 24, 25, 46, 47, 48, 49, 50, 51, 52, 53, 59, 60, 61, 62, 63, 66, 69, 70, 72, 73, Non-swapped-domain interface residues and interactions: Chains Residues A 0, 1, 6, 7, 10, 19, 28, 29, 31, 32, 36, 39, 40, 43, B 7, 10, 19, 28, 29, 31, 32, 36, 39, 40, 43, 45,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	MET(43)PRO,	ASN(22)GLN,	MET(43)PRO,	No mutation
B	MET(43)PRO,	ASN(22)GLN,	MET(43)PRO,	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:1HT9

B:1HT9

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	1HT9.ali
atm file:	1HT9.atm
cof file:	1HT9.cof
hbd file:	1HT9.hbd
html file:	1HT9.html
pdb file:	1HT9.pdb
ps file:	1HT9.ps
psa file:	1HT9.psa
rtf file:	1HT9.rtf
sst file:	1HT9.sst
tem file:	1HT9.tem