3DSwap | Knowledgebase of 3D Domain Swapping in Proteins

Pfam Domains mapped on to the structure: 1H9T

No. Chain ID Pfam ID Pfam Description Linkout - Pfam Linkout - CDD

1 A PF00392 Bacterial regulatory proteins, gntR family PF00392 PF00392

2 A PF07840 FadR C-terminal domain PF07840 PF07840

Gene Ontology Annotations: 1H9T

No. GO ID GO Description Linkout - AmiGO

1 GO:0019217 regulation of fatty acid metabolic process GO:0019217

Conserved Domain Database Superfamily Annotations: 1H9T

No. PDB ID PSSM ID CDD Accession Superfamily Short Name Linkout - CDD

1 1H9T 153418 cd07377 WHTH_GntR - cl00088

2 1H9T 212173 cl00088 HTH superfamily - -

3 1H9T 209375 cl11656 FCD superfamily - -

4 1H9T 209375 cl11656 FCD superfamily - -

Structural Details of PDB entry 1H9T

Structural Details of PDB entry 1H9T

PDBid Chains Hinge Swapped Domain

1H9T A,B A:86-91,B:86-91 A:5-85,B:5-85

Swapped-domain interface residues and interactions:

Chains Residues
A 7, 8, 9, 13, 33, 34, 35, 42, 43, 44, 45, 46, 47, 49, 50, 53, 54, 57, 58, 63, 65, 66, 67, 68, 69, 75, 76, 78, 79, 80, 81, 82, 83, 163, 164, 166, 167,

B 7, 8, 9, 13, 33, 34, 35, 42, 44, 45, 46, 47, 49, 50, 53, 54, 57, 58, 63, 65, 66, 67, 68, 69, 75, 76, 78, 79, 80, 81, 82, 83, 163, 164, 166, 167,

Non-swapped-domain interface residues and interactions:

Chains Residues
A 100, 101, 103, 104, 107, 108, 111, 114, 150, 154, 157, 158, 159, 160, 161, 213, 238, 239,

B 97, 100, 101, 103, 104, 107, 108, 111, 114, 123, 150, 154, 157, 158, 159, 160, 161, 230,

X 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19,

Y 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18,

Swapped domains are represented using trasperent spheres.
Non-swapped part is reprented using light color and cartoon reprentation.
Hinge region is shown in yellow color.

Mutations in critical regions:

Chains Hinge Domain swapped interface Non-swapped interface Swapped Domain

A No mutation No mutation No mutation No mutation

B No mutation No mutation No mutation No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

3:1H9T A:1H9T B:1H9T

JOY Structural annotation for hinge hinge and swapped domain:

Hinge Swapped domain

JOY output:

ali file: 1H9T.ali
atm file: 1H9T.atm
pdb file: 1H9T.pdb
psa file: 1H9T.psa
sst file: 1H9T.sst