3DSwap | Knowledgebase of 3D Domain Swapping in Proteins

Pfam Domains mapped on to the structure: 1H4V

No. Chain ID Pfam ID Pfam Description Linkout - Pfam Linkout - CDD

1 B PF03129 Anticodon binding domain PF03129 PF03129

Conserved Domain Database Superfamily Annotations: 1H4V

No. PDB ID PSSM ID CDD Accession Superfamily Short Name Linkout - CDD

1 1H4V 73226 cd00773 HisRS-like_core - cl00268

2 1H4V 206944 cl00268 class_II_aaRS-like_core superfamily - -

3 1H4V 29797 cd00738 HGTP_anticodon - cl00266

4 1H4V 206943 cl00266 HGTP_anticodon superfamily - -

5 1H4V 206943 cl00266 HGTP_anticodon superfamily - -

Structural Details of PDB entry 1H4V

Structural Details of PDB entry 1H4V

PDBid Chains Hinge Swapped Domain

1H4V A,B A:321-330,B:321-330 A:331-421,B:331-421

Swapped-domain interface residues and interactions:

Chains Residues
A 29, 30, 33, 34, 35, 247, 341, 342, 343, 345, 346, 349, 352, 353, 356, 358, 359, 361, 376, 421,

B 29, 30, 33, 34, 35, 247, 341, 342, 343, 345, 346, 349, 352, 353, 356, 358, 359, 361, 376,

Non-swapped-domain interface residues and interactions:

Chains Residues
A 2, 3, 4, 5, 6, 7, 9, 10, 11, 12, 13, 14, 17, 21, 28, 32, 37, 38, 39, 40, 42, 43, 44, 45, 46, 48, 49, 63, 66, 68, 70, 71, 74, 76, 78, 88, 91, 92, 93, 98, 99, 101, 103, 109, 111, 113, 115, 116, 122, 123, 136, 138, 142, 145, 146, 149, 153, 242, 243, 246, 295, 296, 326,

B 2, 3, 4, 5, 6, 7, 9, 10, 11, 12, 13, 14, 17, 21, 28, 32, 37, 38, 39, 40, 42, 43, 44, 45, 46, 48, 49, 63, 66, 68, 70, 71, 74, 76, 78, 88, 91, 92, 93, 98, 99, 101, 103, 109, 111, 113, 115, 116, 122, 123, 136, 138, 142, 145, 146, 149, 153, 242, 243, 246, 295, 296, 326,

Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.

Mutations in critical regions:

Chains Hinge Domain swapped interface Non-swapped interface Swapped Domain

A No mutation No mutation No mutation No mutation

B No mutation No mutation No mutation No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:1H4V B:1H4V

JOY Structural annotation for hinge hinge and swapped domain:

Hinge Swapped domain

JOY output:

ali file: 1H4V.ali
atm file: 1H4V.atm
cof file: 1H4V.cof
hbd file: 1H4V.hbd
html file: 1H4V.html
pdb file: 1H4V.pdb
ps file: 1H4V.ps
psa file: 1H4V.psa
rtf file: 1H4V.rtf
sst file: 1H4V.sst
tem file: 1H4V.tem