Pfam Domains mapped on to the structure: 1GUT

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF03459	TOBE domain	PF03459	PF03459

Conserved Domain Database Superfamily Annotations: 1GUT

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	1GUT	207413	cl01440	TOBE_2	superfamily - -

Structural Details of PDB entry 1GUT PDBid Chains Hinge Swapped Domain 1GUT A,D A:60-64,D:60-64 A:65-68,D:65-68 Swapped-domain interface residues and interactions: Chains Residues A 37, 39, 47, 55, 56, 57, 58, 59, 65, 66, 67, 68, B 4, 60, D 37, 39, 47, 55, 56, 57, 58, 59, 65, 66, 67, 68, E 2, 3, 4, 5, Non-swapped-domain interface residues and interactions: Chains Residues A 2, 3, 4, 5, 6, 7, 8, 9, 17, 18, 19, 20, 21, 22, 24, 25, 29, 30, 31, 33, 34, 35, 36, 38, 40, 42, 43, 46, 60, 61, 62, 63, 64, B 2, 3, 5, 6, 7, 8, 9, 17, 18, 19, 20, 21, 22, 24, 29, 30, 31, 33, 34, 35, 36, 37, 38, 39, 40, 42, 43, 46, 47, 55, 56, 57, 58, 59, 61, 62, 63, 64, 65, 66, 67, 68, C 2, 3, 4, 5, 6, 7, 8, 9, 14, 17, 18, 19, 20, 21, 22, 24, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 42, 43, 46, 47, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, D 2, 3, 4, 5, 6, 7, 9, 17, 18, 19, 20, 21, 22, 24, 27, 29, 30, 31, 33, 34, 35, 36, 38, 40, 42, 43, 46, 60, 61, 62, 63, 64, E 6, 7, 9, 17, 19, 20, 21, 22, 24, 26, 29, 30, 31, 33, 34, 35, 36, 37, 38, 39, 40, 42, 43, 46, 47, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, F 2, 3, 4, 5, 6, 7, 9, 17, 18, 19, 20, 21, 22, 24, 27, 29, 30, 31, 33, 34, 35, 36, 37, 38, 39, 40, 42, 43, 46, 47, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, G 2, 3, 4, 5, 6, 7, 8, 9, 14, 17, 18, 19, 20, 21, 22, 24, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 42, 43, 46, 47, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, H 2, 3, 4, 5, 6, 7, 8, 9, 17, 18, 19, 20, 21, 22, 24, 29, 30, 31, 33, 34, 35, 36, 37, 38, 39, 40, 42, 43, 46, 47, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, I 2, 3, 4, 5, 6, 7, 8, 9, 17, 18, 19, 20, 21, 22, 24, 25, 29, 30, 31, 33, 34, 35, 36, 37, 38, 39, 40, 42, 43, 46, 47, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, J 2, 3, 4, 5, 6, 7, 9, 17, 19, 20, 21, 22, 24, 26, 29, 30, 31, 33, 34, 35, 36, 37, 38, 39, 40, 42, 43, 46, 47, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, K 2, 3, 4, 5, 6, 7, 9, 17, 18, 19, 20, 21, 22, 24, 27, 29, 30, 31, 33, 34, 35, 36, 37, 38, 39, 40, 42, 43, 46, 47, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, L 2, 3, 4, 5, 6, 7, 9, 17, 18, 19, 20, 21, 22, 24, 27, 29, 30, 31, 33, 34, 35, 36, 37, 38, 39, 40, 42, 43, 46, 47, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67,

Swapped domains are represented using trasperent spheres. Non-swapped part is reprented using light color and cartoon reprentation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	No mutation	No mutation	No mutation
D	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

3:1GUT

A:1GUT

L:1GUT

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	1GUT.ali
atm file:	1GUT.atm
cof file:	1GUT.cof
hbd file:	1GUT.hbd
html file:	1GUT.html
pdb file:	1GUT.pdb
ps file:	1GUT.ps
psa file:	1GUT.psa
rtf file:	1GUT.rtf
sst file:	1GUT.sst
tem file:	1GUT.tem