Pfam Domains mapped on to the structure: 1FLO

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF03930	Recombinase Flp protein N-terminus	PF03930	PF03930
2	A	PF05202	Recombinase Flp protein	PF05202	PF05202

Conserved Domain Database Superfamily Annotations: 1FLO

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	1FLO	29494	cd00217	INT_Flp -	cl00213
2	1FLO	211431	cl00213	DNA_BRE_C	superfamily - -

Structural Details of PDB entry 1FLO PDBid Chains Hinge Swapped Domain 1FLO A,D,C,B A:107-115,D:108-114,C:108-114,B:107-115;A:129-136,D:134-136,C:134-136,B:129-136 A:116-128,D:115-133,C:115-133,B:116-128 Swapped-domain interface residues and interactions: Chains Residues A 11, 12, 13, 45, 48, 49, 92, 116, 119, 120, 123, 124, 127, 264, B 11, 12, 13, 45, 48, 49, 92, 116, 119, 120, 123, 124, 127, 264, C 11, 12, 13, 45, 48, 49, 92, 115, 116, 117, 119, 120, 123, 124, 127, D 11, 12, 13, 45, 48, 49, 92, 115, 116, 117, 119, 120, 123, 124, 127, Non-swapped-domain interface residues and interactions: Chains Residues A 2, 3, 9, 16, 41, 43, 44, 47, 53, 55, 56, 58, 59, 60, 62, 65, 66, 82, 83, 84, 85, 88, 95, 96, 107, 114, 137, 141, 144, 145, 148, 154, 168, 170, 171, 173, 174, 178, 191, 192, 193, 223, 224, 269, 278, 280, 281, 282, 284, 285, 286, 288, 289, 299, 300, 301, 303, 304, 305, 308, 309, 312, 313, 316, 317, 319, 321, 322, 324, 325, 330, 331, 333, 341, 342, 343, 344, 345, 366, 367, 368, 369, 423, B 2, 3, 9, 16, 41, 43, 44, 47, 53, 55, 56, 58, 59, 60, 62, 65, 66, 82, 83, 84, 85, 88, 95, 96, 107, 109, 111, 112, 114, 137, 141, 144, 145, 148, 154, 168, 170, 171, 174, 178, 191, 192, 193, 222, 223, 224, 267, 269, 278, 280, 281, 282, 284, 285, 286, 288, 289, 299, 300, 301, 303, 304, 305, 308, 309, 312, 313, 316, 317, 319, 321, 322, 324, 325, 330, 331, 333, 344, 345, 346, 366, 367, 368, 369, 423, C 2, 3, 8, 9, 16, 43, 44, 47, 53, 55, 56, 58, 59, 60, 61, 62, 65, 66, 82, 84, 85, 95, 96, 107, 108, 110, 112, 113, 114, 137, 140, 141, 142, 144, 145, 168, 170, 171, 174, 178, 191, 192, 193, 222, 223, 224, 276, 278, 280, 281, 282, 284, 285, 289, 299, 300, 301, 302, 303, 304, 305, 309, 312, 313, 322, 330, 331, 332, 333, 334, 335, 336, 338, 339, 341, 342, 343, 344, 345, 346, 348, 349, 351, 353, 369, 423, D 2, 3, 8, 9, 16, 43, 44, 47, 53, 55, 56, 58, 59, 60, 62, 65, 66, 82, 84, 85, 95, 96, 107, 108, 110, 113, 114, 141, 142, 144, 145, 168, 169, 170, 171, 174, 178, 191, 192, 193, 222, 223, 224, 276, 278, 280, 281, 282, 284, 285, 289, 299, 300, 301, 303, 304, 305, 313, 322, 331, 332, 333, 334, 335, 336, 338, 339, 341, 342, 343, 344, 345, 346, 348, 349, 351, 353, 369, E 16, 15, 14, 13, 12, 11, 10, 9, 8, 7, 6, 5, F 3, 2, 1, 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, G 17, 16, 15, 14, 13, 12, 11, 10, 9, 8, 7, 6, 5, H 3, 2, 1, 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, I 17, 16, 15, 14, 13, 12, 11, 10, 9, 8, 7, 6, 5, J 3, 2, 1, 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, K 17, 16, 15, 14, 13, 12, 11, 10, 9, 8, 7, 6, 5, L 3, 2, 1, 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	No mutation	No mutation	No mutation
D	No mutation	No mutation	No mutation	No mutation
C	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation
D	No mutation	No mutation	No mutation	No mutation
C	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:1FLO

B:1FLO

C:1FLO

D:1FLO

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	1FLO.ali
atm file:	1FLO.atm
pdb file:	1FLO.pdb
psa file:	1FLO.psa
sst file:	1FLO.sst