3DSwap | Knowledgebase of 3D Domain Swapping in Proteins

Pfam Domains mapped on to the structure: 1FDL

No. Chain ID Pfam ID Pfam Description Linkout - Pfam Linkout - CDD

1 L PF13895 Immunoglobulin domain PF13895 PF13895

2 L PF13927 Immunoglobulin domain PF13927 PF13927

3 L PF00047 Immunoglobulin domain PF00047 PF00047

4 Y PF00062 C-type lysozyme/alpha-lactalbumin family PF00062 PF00062

5 Y PF01464 Transglycosylase SLT domain PF01464 PF01464

Conserved Domain Database Superfamily Annotations: 1FDL

No. PDB ID PSSM ID CDD Accession Superfamily Short Name Linkout - CDD

1 1FDL 29018 cd00119 LYZ1 - cl00222

2 1FDL 212597 cl00222 lysozyme_like superfamily - -

Structural Details of PDB entry 1FDL

Structural Details of PDB entry 1FDL

PDBid Chains Hinge Swapped Domain

1FDL H,L H:42-46,L:41-45 H:1-41,L:1-40

Swapped-domain interface residues and interactions:

Chains Residues
H 39,

L 1, 32, 36, 38,

Non-swapped-domain interface residues and interactions:

Chains Residues
H 44, 45, 47, 50, 58, 61, 94, 98, 101, 102, 103, 104, 106, 107, 108, 125, 126, 127, 128, 129, 130, 131, 140, 142, 144, 146, 167, 168, 169, 170, 172, 174, 179, 181, 183, 211, 216, 217,

L 43, 44, 46, 49, 87, 89, 91, 94, 95, 96, 98, 100, 114, 116, 118, 119, 120, 121, 122, 123, 124, 127, 131, 133, 135, 137, 138, 158, 160, 161, 162, 163, 164, 167, 174, 176, 178, 180, 214,

Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.

Mutations in critical regions:

Chains Hinge Domain swapped interface Non-swapped interface Swapped Domain

H No mutation No mutation No mutation No mutation

L No mutation No mutation GLN(89)HIS, ARG(96)TRP, PHE(118)LEU, No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

H:1FDL

JOY Structural annotation for hinge hinge and swapped domain:

Hinge Swapped domain

JOY output:

ali file: 1FDL.ali
atm file: 1FDL.atm
cof file: 1FDL.cof
hbd file: 1FDL.hbd
html file: 1FDL.html
pdb file: 1FDL.pdb
ps file: 1FDL.ps
psa file: 1FDL.psa
rtf file: 1FDL.rtf
sst file: 1FDL.sst
tem file: 1FDL.tem