Pfam Domains mapped on to the structure: 1F61

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF00463	Isocitrate lyase family	PF00463	PF00463
2	A	PF00463	Isocitrate lyase family	PF00463	PF00463
3	A	PF13714	Phosphoenolpyruvate phosphomutase	PF13714	PF13714

Conserved Domain Database Superfamily Annotations: 1F61

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	1F61	119341	cd06556	ICL_KPHMT -	cl00435
2	1F61	212216	cl00435	ICL_KPHMT	superfamily - -

Structural Details of PDB entry 1F61 PDBid Chains Hinge Swapped Domain 1F61 A,D,C,B A:346-348,D:346-348,C:346-348,B:346-348 A:349-418,D:349-384,C:349-384,B:349-418 Swapped-domain interface residues and interactions: Chains Residues A 75, 76, 79, 80, 83, 84, 85, 97, 105, 106, 107, 191, 320, 329, 330, 333, 349, 351, 352, 353, 354, 355, 356, 357, 358, 359, 360, 361, 362, 363, 365, 366, 369, 370, 371, 373, 374, 376, 377, 378, 379, 380, 381, 383, 386, 388, 390, 391, 393, 394, 396, 397, 399, 402, 403, 406, 407, 410, 412, 418, B 75, 76, 79, 80, 83, 84, 85, 97, 105, 106, 107, 191, 320, 321, 329, 330, 333, 349, 351, 352, 353, 354, 355, 356, 357, 358, 359, 360, 361, 362, 363, 365, 366, 369, 370, 371, 373, 374, 376, 377, 378, 379, 380, 381, 383, 386, 388, 390, 391, 393, 394, 396, 397, 399, 402, 403, 406, 407, 412, Non-swapped-domain interface residues and interactions: Chains Residues A 65, 67, 69, 73, 93, 98, 103, 104, 109, 111, 123, 126, 130, 255, 316, 317, 319, 321, 346, 348, B 65, 67, 69, 73, 93, 98, 103, 104, 109, 111, 123, 126, 130, 189, 255, 314, 316, 317, 319, 346, 348,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	No mutation	No mutation	No mutation
D	No mutation	No mutation	No mutation	No mutation
C	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:1F61

B:1F61

C:1F61

D:1F61

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	1F61.ali
atm file:	1F61.atm
cof file:	1F61.cof
hbd file:	1F61.hbd
html file:	1F61.html
pdb file:	1F61.pdb
ps file:	1F61.ps
psa file:	1F61.psa
rtf file:	1F61.rtf
sst file:	1F61.sst
tem file:	1F61.tem