3DSwap | Knowledgebase of 3D Domain Swapping in Proteins

Pfam Domains mapped on to the structure: 1F5V

No. Chain ID Pfam ID Pfam Description Linkout - Pfam Linkout - CDD

1 A PF00881 Nitroreductase family PF00881 PF00881

Conserved Domain Database Superfamily Annotations: 1F5V

No. PDB ID PSSM ID CDD Accession Superfamily Short Name Linkout - CDD

1 1F5V 48392 cd02146 NfsA_FRP - cl00514

2 1F5V 207085 cl00514 Nitro_FMN_reductase superfamily - -

Structural Details of PDB entry 1F5V

Structural Details of PDB entry 1F5V

PDBid Chains Hinge Swapped Domain

1F5V A,B A:220-227,B:220-227 A:228-240,B:228-240

Swapped-domain interface residues and interactions:

Chains Residues
A 98, 99, 228, 229, 232, 238, 240,

B 98, 99, 228, 229, 232, 238,

Non-swapped-domain interface residues and interactions:

Chains Residues
A 1, 2, 4, 5, 8, 9, 11, 13, 25, 26, 29, 31, 32, 33, 35, 36, 37, 38, 41, 42, 43, 44, 46, 47, 48, 49, 50, 52, 53, 56, 82, 85, 86, 88, 89, 90, 92, 93, 94, 97, 100, 101, 102, 103, 105, 106, 109, 110, 111, 113, 114, 117, 118, 121, 122, 128, 133, 143, 144, 146, 152, 153, 167, 169, 170, 171, 172, 174, 175, 176, 177, 178, 179, 180, 181, 183, 184, 212, 213, 215, 216, 217, 219, 220, 221, 222, 223, 224, 225, 226,

B 1, 2, 4, 5, 8, 9, 11, 13, 25, 26, 29, 31, 32, 33, 35, 36, 37, 38, 41, 42, 43, 44, 46, 47, 48, 49, 50, 52, 53, 56, 82, 85, 86, 88, 89, 90, 92, 93, 94, 97, 100, 101, 102, 103, 105, 106, 109, 110, 111, 113, 114, 117, 118, 121, 122, 128, 133, 143, 144, 146, 149, 152, 153, 167, 169, 170, 171, 172, 174, 175, 176, 177, 178, 179, 180, 181, 183, 184, 189, 212, 213, 215, 216, 217, 219, 220, 221, 222, 223, 224, 225, 226,

Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.

Mutations in critical regions:

Chains Hinge Domain swapped interface Non-swapped interface Swapped Domain

A No mutation No mutation No mutation No mutation

B No mutation No mutation No mutation No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:1F5V B:1F5V

JOY Structural annotation for hinge hinge and swapped domain:

Hinge Swapped domain

JOY output:

ali file: 1F5V.ali
atm file: 1F5V.atm
cof file: 1F5V.cof
hbd file: 1F5V.hbd
html file: 1F5V.html
pdb file: 1F5V.pdb
ps file: 1F5V.ps
psa file: 1F5V.psa
rtf file: 1F5V.rtf
sst file: 1F5V.sst
tem file: 1F5V.tem