3DSwap | Knowledgebase of 3D Domain Swapping in Proteins

Pfam Domains mapped on to the structure: 1F0Y

No. Chain ID Pfam ID Pfam Description Linkout - Pfam Linkout - CDD

1 A PF01262 Alanine dehydrogenase/PNT, C-terminal domain PF01262 PF01262

2 A PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PF02737 PF02737

3 A PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus PF01210 PF01210

4 A PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain PF00725 PF00725

Conserved Domain Database Superfamily Annotations: 1F0Y

No. PDB ID PSSM ID CDD Accession Superfamily Short Name Linkout - CDD

1 1F0Y 212616 cl09931 NADB_Rossmann superfamily - -

2 1F0Y 201415 cl08285 3HCDH superfamily - -

3 1F0Y 201415 cl08285 3HCDH superfamily - -

Structural Details of PDB entry 1F0Y

Structural Details of PDB entry 1F0Y

PDBid Chains Hinge Swapped Domain

1F0Y A,B A:241-244,B:241-244 A:245-302,B:245-302

Swapped-domain interface residues and interactions:

Chains Residues
A 273, 274, 302,

B 273, 274,

Non-swapped-domain interface residues and interactions:

Chains Residues
A 160, 166, 167, 168, 195, 197, 200, 202, 206, 207, 209, 210, 211, 213, 214, 217, 218, 221, 224, 225, 226, 227, 231, 232, 234, 235, 236, 238, 239, 240, 241, 242, 243,

B 160, 166, 167, 168, 195, 197, 200, 202, 206, 207, 209, 210, 211, 214, 217, 218, 221, 224, 225, 226, 227, 231, 232, 234, 235, 236, 238, 239, 240, 241, 242, 243,

Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.

Mutations in critical regions:

Chains Hinge Domain swapped interface Non-swapped interface Swapped Domain

A No mutation No mutation No mutation No mutation

B No mutation No mutation No mutation No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:1F0Y B:1F0Y

JOY Structural annotation for hinge hinge and swapped domain:

Hinge Swapped domain

JOY output:

ali file: 1F0Y.ali
atm file: 1F0Y.atm
cof file: 1F0Y.cof
hbd file: 1F0Y.hbd
html file: 1F0Y.html
pdb file: 1F0Y.pdb
ps file: 1F0Y.ps
psa file: 1F0Y.psa
rtf file: 1F0Y.rtf
sst file: 1F0Y.sst
tem file: 1F0Y.tem