3DSwap | Knowledgebase of 3D Domain Swapping in Proteins

Pfam Domains mapped on to the structure: 1EXJ

No. Chain ID Pfam ID Pfam Description Linkout - Pfam Linkout - CDD

1 A PF13411 MerR HTH family regulatory protein PF13411 PF13411

2 A PF00376 MerR family regulatory protein PF00376 PF00376

Conserved Domain Database Superfamily Annotations: 1EXJ

No. PDB ID PSSM ID CDD Accession Superfamily Short Name Linkout - CDD

1 1EXJ 133382 cd01107 HTH_BmrR - cl02600

2 1EXJ 207663 cl02600 HTH_MerR-SF superfamily - -

3 1EXJ 207387 cl01368 GyrI-like superfamily - -

4 1EXJ 207387 cl01368 GyrI-like superfamily - -

Structural Details of PDB entry 1EXJ

Structural Details of PDB entry 1EXJ

PDBid Chains Hinge Swapped Domain

1EXJ A,B A:92-101,B:92-101 A:3-91,B:3-91

Swapped-domain interface residues and interactions:

Chains Residues
A 4, 6, 13, 14, 16, 30, 47, 48, 50, 51, 52, 54, 55, 57, 58, 61, 62, 73, 74, 75, 76, 77, 78, 80, 81, 84, 85, 88, 91, 98, 102, 109, 148, 149, 150, 153, 157, 164, 165, 166, 258, 259, 260, 261,

B 4, 6, 13, 14, 16, 30, 47, 48, 50, 51, 52, 54, 55, 57, 58, 61, 62, 73, 74, 75, 76, 77, 78, 80, 81, 84, 85, 88, 91, 98, 102, 109, 148, 149, 150, 153, 157, 164, 165, 166, 258, 259, 260, 261,

Non-swapped-domain interface residues and interactions:

Chains Residues
A 92, 94, 95, 97, 99, 101, 105, 108, 112, 113, 116, 160, 163, 167, 170, 257, 262, 263, 266, 268, 277,

B 92, 94, 95, 97, 99, 101, 105, 108, 112, 113, 116, 160, 163, 167, 170, 257, 262, 263, 266, 268,

Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.

Mutations in critical regions:

Chains Hinge Domain swapped interface Non-swapped interface Swapped Domain

A No mutation No mutation No mutation No mutation

B No mutation No mutation No mutation No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:1EXJ B:1EXJ

JOY Structural annotation for hinge hinge and swapped domain:

Hinge Swapped domain

JOY output:

ali file: 1EXJ.ali
atm file: 1EXJ.atm
cof file: 1EXJ.cof
hbd file: 1EXJ.hbd
html file: 1EXJ.html
pdb file: 1EXJ.pdb
ps file: 1EXJ.ps
psa file: 1EXJ.psa
rtf file: 1EXJ.rtf
sst file: 1EXJ.sst
tem file: 1EXJ.tem