Pfam Domains mapped on to the structure: 1EFV
Conserved Domain Database Superfamily Annotations: 1EFV
Structural Details of PDB entry 1EFV
Structural Details of PDB entry 1EFV
PDBid
Chains
Hinge
Swapped Domain
1EFV
A,B
A:150-156,B:167-172
A:20-149,B:173-255
Swapped-domain interface residues and interactions:
Chains
Residues
A
86 , 88 , 89 , 90 , 113 , 114 , 117 , 118 , 121 , 122 , 125 , 126 , 128 , 129 , 130 , 131 , 132 , 133 , 146 , 148 , 149 , 152 , 153 , 154 , 155 , 156 , 157 , 158 , 159 , 160 , 161 , 196 , 197 , 198 , 199 , 200 , 274 , 309 , 310 , 311 , 312 , 313 , 314 , 315 , 322 , 325 , 326 ,
B
102 , 127 , 128 , 129 , 130 , 131 , 132 , 133 , 136 , 137 , 140 , 141 , 145 , 166 , 167 , 173 , 174 , 175 , 176 , 185 , 186 , 221 , 222 , 223 , 224 , 225 , 226 , 227 , 228 , 230 , 231 , 233 , 234 , 235 , 236 , 237 , 238 , 239 , 242 , 243 , 245 , 246 , 248 , 249 , 252 , 254 ,
Non-swapped-domain interface residues and interactions:
Chains
Residues
A
150 , 151 , 195 , 201 , 202 , 203 , 204 , 205 , 217 , 241 , 249 , 252 , 253 , 259 , 260 , 265 , 266 , 268 , 273 , 284 , 285 , 291 , 293 , 294 , 295 , 297 , 303 , 308 , 316 , 329 , 330 , 331 ,
B
14 , 16 , 17 , 18 , 19 , 20 , 29 , 41 , 106 , 124 , 125 , 143 , 146 , 149 , 159 , 164 , 165 , 168 , 169 , 170 , 171 , 172 ,
Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.
Mutations in critical regions:
Chains
Hinge
Domain swapped interface
Non-swapped interface
Swapped Domain
A No mutation No mutation No mutation No mutation
B No mutation No mutation No mutation No mutation
HIDE output:
JMOL Visualization:
2D-plot:
JOY Structural annotation for hinge hinge and swapped domain:
JOY output: