Pfam Domains mapped on to the structure: 1EAP

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF13895	Immunoglobulin domain	PF13895	PF13895
2	B	PF13895	Immunoglobulin domain	PF13895	PF13895

Conserved Domain Database Superfamily Annotations: 1EAP

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	1EAP	143182	cd04981	IgV_H -	cl11960
2	1EAP	212623	cl11960	Ig	superfamily - -
3	1EAP	143186	cd04985	IgC_CH1 -	cl11960
4	1EAP	212623	cl11960	Ig	superfamily - -
5	1EAP	212623	cl11960	Ig	superfamily - -

Structural Details of PDB entry 1EAP PDBid Chains Hinge Swapped Domain 1EAP A,B A:40-45,B:41-46 A:1-39,B:1-40 Swapped-domain interface residues and interactions: Chains Residues A 1, 9, 36, 38, B 35, 37, 39, Non-swapped-domain interface residues and interactions: Chains Residues A 43, 44, 46, 49, 55, 56, 85, 87, 94, 96, 98, 100, 103, 116, 118, 119, 121, 123, 124, 127, 131, 133, 135, 137, 138, 158, 160, 161, 162, 163, 164, 165, 167, 174, 176, 178, 180, 214, B 42, 43, 44, 45, 47, 50, 59, 62, 95, 100, 102, 103, 104, 110, 112, 114, 133, 134, 135, 136, 137, 138, 139, 148, 150, 152, 154, 175, 176, 177, 178, 180, 182, 187, 189, 191, 219,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	No mutation	LEU(55)GLN,	LEU(4)MET, THR(22)ALA, SER(26)ASN, LYS(30)ASN, GLY(34)ALA,
B	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:1EAP

B:1EAP

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	1EAP.ali
atm file:	1EAP.atm
cof file:	1EAP.cof
hbd file:	1EAP.hbd
html file:	1EAP.html
pdb file:	1EAP.pdb
ps file:	1EAP.ps
psa file:	1EAP.psa
rtf file:	1EAP.rtf
sst file:	1EAP.sst
tem file:	1EAP.tem