3DSwap | Knowledgebase of 3D Domain Swapping in Proteins

Pfam Domains mapped on to the structure: 1E51

No. Chain ID Pfam ID Pfam Description Linkout - Pfam Linkout - CDD

1 A PF00490 Delta-aminolevulinic acid dehydratase PF00490 PF00490

Conserved Domain Database Superfamily Annotations: 1E51

No. PDB ID PSSM ID CDD Accession Superfamily Short Name Linkout - CDD

1 1E51 88600 cd04824 eu_ALAD_PBGS_cysteine_rich - cl00338

2 1E51 198575 cl00338 ALAD_PBGS superfamily - -

Structural Details of PDB entry 1E51

Structural Details of PDB entry 1E51

PDBid Chains Hinge Swapped Domain

1E51 A,B A:23-30,B:23-30 A:1-22,B:1-22

Swapped-domain interface residues and interactions:

Chains Residues
A 1, 4, 5, 6, 7, 8, 10, 11, 12, 17, 20, 21, 172, 173, 223, 224, 227, 229, 230, 240,

B 1, 4, 5, 6, 7, 8, 10, 11, 12, 17, 20, 21, 172, 173, 223, 224, 227, 229, 230, 240,

Non-swapped-domain interface residues and interactions:

Chains Residues
A 24, 143, 144, 147, 171, 202, 203, 204, 206, 207, 220, 222, 226, 228, 231, 233, 236, 237, 243, 244, 255, 256, 257, 258, 259, 262, 263, 280, 283, 284, 285, 287, 288, 291, 293, 294, 298, 299, 302, 305, 306, 309, 310, 328,

B 147, 170, 171, 176, 202, 203, 204, 206, 207, 222, 226, 228, 231, 232, 233, 236, 237, 243, 244, 255, 256, 257, 258, 259, 262, 263, 280, 283, 284, 285, 287, 288, 291, 293, 294, 298, 299, 302, 305, 306, 309, 310,

Swapped domains are represented using trasperent spheres.
Non-swapped part is reprented using light color and cartoon reprentation.
Hinge region is shown in yellow color.

Mutations in critical regions:

Chains Hinge Domain swapped interface Non-swapped interface Swapped Domain

A No mutation No mutation No mutation No mutation

B No mutation No mutation No mutation No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

3:1E51 A:1E51 B:1E51

JOY Structural annotation for hinge hinge and swapped domain:

Hinge Swapped domain

JOY output:

ali file: 1E51.ali
atm file: 1E51.atm
cof file: 1E51.cof
hbd file: 1E51.hbd
html file: 1E51.html
pdb file: 1E51.pdb
ps file: 1E51.ps
psa file: 1E51.psa
rtf file: 1E51.rtf
sst file: 1E51.sst
tem file: 1E51.tem